Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | QPCTL | Q9NXS2 | 3/20 | 0.39 |
| ▸ | QPCT | Q16769 | 2/20 | 0.39 |
| ▸ | CSF1R | P07333 | 3/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3598037 | 0.88 | CXCR2 (0.47) | QPCTLQPCTMEN1KMT2ADPP4 | |
| SCHEMBL3600972 | 0.85 | DPP4 (0.41) | MEN1KMT2ADPP4CNR1GAA | |
| SCHEMBL3595008 | 0.84 | CXCR2 (0.50) | YTHDC1ROCK2DPP4CXCR2LMNA | |
| SCHEMBL3605962 | 0.84 | DPP4 (0.41) | TTRYTHDC1S1PR1S1PR5QPCTL | |
| SCHEMBL3600416 | 0.84 | CNR1 (0.42) | QPCTLQPCTDPP4CNR1 | |
| SCHEMBL3593028 | 0.83 | ALDH1A1 (0.44) | DPP4CXCR2CNR1GAA | |
| SCHEMBL3601694 | 0.83 | BCL2L2 (0.45) | YTHDC1DPP4SMN1; SMN2 | |
| SCHEMBL3605710 | 0.82 | MEN1 (0.40) | MEN1KMT2ADPP4CXCR2CNR1 | |
| SCHEMBL3592478 | 0.78 | P2RX7 (0.44) | DPP4 | |
| SCHEMBL3605612 | 0.77 | CNR1 (0.43) | DPP4CNR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |