Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 15/20 | 0.57 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.57 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4435598 | 0.82 | SCD (0.77) | SCDSCD5 | |
| SCHEMBL3606618 | 0.73 | SCD (1.00) | SCDSCD5 | |
| SCHEMBL3605024 | 0.70 | SCD (1.00) | SCDSCD5 | |
| SCHEMBL3606321 | 0.70 | SCD (0.80) | SCDSCD5 | |
| SCHEMBL3609521 | 0.70 | SCD (1.00) | SCDSCD5 | |
| SCHEMBL13730861 | 0.67 | SCD (0.53) | SCDSCD5 | |
| SCHEMBL3599831 | 0.67 | SCD (1.00) | SCDSCD5 | |
| SCHEMBL3605058 | 0.66 | SCD (0.79) | SCDSCD5 | |
| SCHEMBL3610488 | 0.66 | SCD (1.00) | SCDSCD5 | |
| SCHEMBL4502364 | 0.66 | SCD (0.60) | SCDSCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056505-A1 | Substituted Pyrazalones | BIOGEN IDEC MA INC. | 2010-03-04 | — | — | US | disclosed |
| US-20100004245-A1 | AZACYCLOALKANE DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | MERCK FROSST CANADA LTD. (CA) | 2010-01-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056505-A1 | Substituted Pyrazalones | ACVR1, ACVRL1, TGFBR1 | SCD 4135/4885SCD5 1575/4885IDO1 666/4885 |
| US-20100004245-A1 | AZACYCLOALKANE DERIVATIVES AS INHIBITORS OF STEAROYL-COENZYME A DELTA-9 DESATURASE | SCD, SCD5, SREBF1 | SCD 1/4885SCD5 2/4885IDO1 1281/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.