Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3606936 | 0.81 | MAPT (0.36) | L3MBTL1KDM4EKMT2AHPGDALDH1A1 | |
| SCHEMBL8764071 | 0.79 | KCNK3 (0.44) | KCNK3KCNK9ARL3MBTL1CTSS | |
| SCHEMBL7029811 | 0.78 | KDM4E (0.46) | PDK2KDM4EKMT2AALDH1A1HSD17B10 | |
| SCHEMBL10735199 | 0.76 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1CA12CA1CA2 | |
| SCHEMBL38661865 | 0.76 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1CA12CA1CA2 | |
| SCHEMBL6545206 | 0.74 | S1PR1 (0.33) | ARKMT2AMRGPRX4 | |
| SCHEMBL7025722 | 0.73 | ALDH1A1 (0.46) | L3MBTL1PDK2KDM4EALDH1A1HSD17B10 | |
| SCHEMBL13345675 | 0.73 | KCNK3 (0.44) | KCNK3KCNK9ARL3MBTL1CTSS | |
| SCHEMBL7030243 | 0.73 | PDK2 (0.39) | CTSSPDK2KDM4EKMT2ACA1 | |
| SCHEMBL8854436 | 0.72 | KCNK3 (0.39) | KCNK3KCNK9ARL3MBTL1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723266-B2 | Substituted aryl sulphony(thio)ureas used as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-25 | — | — | US | disclosed |
| US-7723266-B2 | Substituted aryl sulphony(thio)ureas used as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-25 | — | — | US | disclosed |
| EP-0885200-B1 | SUBSTITUTED ARYL SULPHONYL(THIO)UREAS USED AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2008-05-21 | — | — | EP | disclosed |
| EP-1683789-A1 | Substituted arylsulfonyl(thio)ureas as herbicides | Bayer CropScience AG (DE) | 2006-07-26 | — | — | EP | disclosed |
| US-20050004123-A1 | Substituted aryl sulphonyl(thio)ureas used as herbicides | BAYER AG (DE) | 2005-01-06 | — | — | US | disclosed |
| US-6838414-B2 | Substituted aryl sulphonyl(thio)ureas used as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2005-01-04 | — | — | US | disclosed |
| US-20030153463-A1 | Substituted aryl sulphonyl(thio)ureas | GESING ERNST RUDOLF F (DE) | 2003-08-14 | — | — | US | disclosed |
| US-6451737-B1 | N-(4,6-DIMETHYL-PYRIMIDIN-2-YL)-N'-(2-METHOXY-6-TRIFLUOROMETHY L-PHENYLSULPHONYL)-UREA | BAYER AKTIENGESELLSCHAFT (DE) | 2002-09-17 | — | — | US | disclosed |
| EP-0885200-A1 | SUBSTITUTED ARYL SULPHONYL(THIO)UREAS USED AS HERBICIDES | BAYER AG (DE) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997032861-A1 | SUBSTITUTED ARYL SULPHONYL(THIO)UREAS USED AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153463-A1 | Substituted aryl sulphonyl(thio)ureas | TST, DDT, CBR3 | KCNK3 965/4885KCNK9 2007/4885AR 3382/4885 |
| US-20050004123-A1 | Substituted aryl sulphonyl(thio)ureas used as herbicides | DDT, CBR3, TST | KCNK3 1288/4885KCNK9 2491/4885AR 3099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.