Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | CTSB | P07858 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7788656 | 0.87 | TDP1 (0.80) | TDP1CTSBALDH1A1ARHSD17B10 | |
| SCHEMBL29475175 | 0.77 | TDP1 (1.00) | TDP1CTSBALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL57166 | 0.77 | TDP1 (1.00) | TDP1CTSBALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL14589059 | 0.76 | MAPT (0.52) | TDP1CTSBALDH1A1PARP1SMN1; SMN2 | |
| SCHEMBL6815901 | 0.75 | TDP1 (0.61) | TDP1CTSBALDH1A1ARHSD17B10 | |
| SCHEMBL7835243 | 0.75 | TDP1 (0.61) | TDP1CTSBALDH1A1ARHSD17B10 | |
| SCHEMBL297029 | 0.75 | TDP1 (0.61) | TDP1CTSBALDH1A1ARHSD17B10 | |
| SCHEMBL1379532 | 0.75 | TDP1 (0.61) | TDP1CTSBALDH1A1ARHSD17B10 | |
| SCHEMBL8722948 | 0.75 | TDP1 (0.61) | TDP1CTSBALDH1A1ARHSD17B10 | |
| SCHEMBL16990730 | 0.75 | TDP1 (0.61) | TDP1CTSBALDH1A1ARHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120058573-A | Synthesis method of 1-tribromomethylsulfonyl naphthalene and derivative thereof | 潍坊学院 | 2025-05-30 | — | — | CN | disclosed |
| US-20230339991-A1 | HYPOXIA-ACTIVATED DNA ALKYLATING AGENT AND MEDICAL USE THEREOF | ASCENTAWITS PHARMACEUTICALS, LTD. (CN) | 2023-10-26 | — | — | US | disclosed |
| EP-1553074-B1 | FUSED BENZENE DERIVATIVE AND USE | TAKEDA PHARMACEUTICAL (JP) | 2014-06-18 | — | — | EP | disclosed |
| US-7649001-B2 | Fused benzene derivative and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-01-19 | — | — | US | disclosed |
| US-20060106067-A1 | Fused benzene derivative and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-05-18 | — | — | US | disclosed |
| CN-1688527-A | Fused benzene derivatives and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2005-10-26 | — | — | CN | disclosed |
| EP-1553074-A1 | FUSED BENZENE DERIVATIVE AND USE | Takeda Pharmaceutical Company Limited (JP) | 2005-07-13 | — | — | EP | disclosed |
| EP-0386116-A1 | PROCESS FOR THE PREPARATION OF COPOLY(ARYLENE SULFIDE) | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1990-09-12 | — | — | EP | disclosed |
| WO-1989004338-A1 | PROCESS FOR THE PREPARATION OF COPOLY(ARYLENE SULFIDE) | EASTMAN KODAK COMPANY (US) | 1989-05-18 | — | — | WO | disclosed |
| US-4792600-A | FROM DIIODOAROMATIC COMPOUND AND SULFUR | EASTMAN KODAK COMPANY (US) | 1988-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060106067-A1 | Fused benzene derivative and use | AR, NR5A1, CBR3 | TDP1 4441/4885CTSB 4422/4885ALDH1A1 1763/4885 |
| US-20230339991-A1 | HYPOXIA-ACTIVATED DNA ALKYLATING AGENT AND MEDICAL USE THEREOF | HIF1AN, HIF1A, MGMT | TDP1 254/4885CTSB 4076/4885ALDH1A1 1217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.