Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | CTSB | P07858 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29643206 | 0.88 | TDP1 (0.75) | TDP1CTSBALDH1A1CYP3A4ALOX15 | |
| SCHEMBL2963038 | 0.88 | TDP1 (0.75) | TDP1CTSBALDH1A1CYP3A4ALOX15 | |
| SCHEMBL7788656 | 0.87 | TDP1 (0.80) | TDP1CTSBALDH1A1ARCYP3A4 | |
| SCHEMBL8819127 | 0.81 | ALDH1A1 (0.52) | TDP1CTSBALDH1A1CYP3A4ALOX15 | |
| SCHEMBL18302010 | 0.78 | ALDH1A1 (0.49) | TDP1CTSBALDH1A1ARCYP3A4 | |
| SCHEMBL17035156 | 0.77 | TDP1 (0.53) | TDP1CTSBALDH1A1CYP3A4ALOX15 | |
| SCHEMBL57166 | 0.77 | TDP1 (1.00) | TDP1CTSBALDH1A1CYP3A4ALOX15 | |
| SCHEMBL29475175 | 0.77 | TDP1 (1.00) | TDP1CTSBALDH1A1CYP3A4ALOX15 | |
| SCHEMBL15845425 | 0.76 | CTSB (0.59) | TDP1CTSBALDH1A1CYP3A4ALOX15 | |
| SCHEMBL246756 | 0.76 | MAPT (0.58) | TDP1ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114685518-B | Organic compounds, mixtures, compositions and organic electronic devices | 广州华睿光电材料有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-111057238-B | Polyimide precursor composition and preparation method and application thereof | 阜阳欣奕华材料科技有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-114685518-A | Organic compound, mixture, composition and organic electronic device | 广州华睿光电材料有限公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-111057238-A | Polyimide precursor composition and preparation method and application thereof | 阜阳欣奕华材料科技有限公司 | 2020-04-24 | — | — | CN | disclosed |
| EP-2997966-A1 | Naphthyl Sulfonamide Pyrrolidine Derivatives as KEAP-1 Modulators for the Treatment of Diabetes, Obesity, Dyslipidemia and Related Disorders | SANOFI (FR) | 2016-03-23 | — | — | EP | disclosed |
| EP-2997966-A1 | Naphthyl Sulfonamide Pyrrolidine Derivatives as KEAP-1 Modulators for the Treatment of Diabetes, Obesity, Dyslipidemia and Related Disorders | SANOFI (FR) | 2016-03-23 | — | — | EP | disclosed |
| WO-1998035982-A1 | COMPOUNDS FOR USE IN ADEPT | ZENECA LIMITED (GB) | 1998-08-20 | — | — | WO | disclosed |