SCHEMBL360684

SCHEMBL360684

CC(C)(C)OC(=O)C=P(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.46
TSHR P16473 3/20 0.37
ALDH1A1 P00352 2/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
AKT1 P31749 2/20 0.36
MAPK10 P53779 1/20 0.36
MEN1 O00255 2/20 0.36
GAA P10253 2/20 0.36
KMT2A Q03164 2/20 0.36
PKM P14618 1/20 0.36
EPHX2 P34913 1/20 0.35
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
POLB P06746 1/20 0.35
BCHE P06276 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL8168614 0.98 HSP90AA1 (0.45) HSP90AA1TSHRALDH1A1HSD17B10TDP1
SCHEMBL22513813 0.83 HSP90AA1 (0.41) HSP90AA1TSHRALDH1A1MEN1GAA
SCHEMBL19687813 0.81 HSP90AA1 (0.32) HSP90AA1AKT1
SCHEMBL12305754 0.79 HSP90AA1 (0.50) HSP90AA1TSHRALDH1A1TDP1AKT1
SCHEMBL12305771 0.79 HSP90AA1 (0.50) HSP90AA1TSHRALDH1A1TDP1AKT1
SCHEMBL9094 0.79 HSP90AA1 (0.50) HSP90AA1TSHRALDH1A1TDP1AKT1
SCHEMBL13908046 0.76 HSP90AA1 (0.47) HSP90AA1TSHRALDH1A1HSD17B10TDP1
SCHEMBL5077963 0.76 HSP90AA1 (0.55) HSP90AA1ALDH1A1HSD17B10TDP1MEN1
SCHEMBL4606197 0.76 HSP90AA1 (0.50) HSP90AA1TSHRALDH1A1MEN1GAA
SCHEMBL2392066 0.75 HSP90AA1 (0.46) HSP90AA1TSHRALDH1A1TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 818 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110721731-B Supported catalyst and preparation method and application thereof 万华化学集团股份有限公司 2022-08-02 CN claimed
CN-106810488-B One class is used as GPR17 and CysLT1Compound of dual antagonist, preparation method and application thereof 中国科学院上海药物研究所 2021-02-19 CN claimed
CN-110721731-A Supported catalyst and preparation method and application thereof 万华化学集团股份有限公司 2020-01-24 CN claimed
CN-106810488-A One class is used as GPR17 and CysLT1The compound of dual antagonist, Preparation Method And The Use 中国科学院上海药物研究所 2017-06-09 CN claimed
EP-2074210-A2 INTEGRATION OF SAMPLE STORAGE AND SAMPLE MANAGEMENT FOR LIFE SCIENCE Biomatrica, INC. (US) 2009-07-01 EP claimed
WO-2009038853-A2 INTEGRATION OF SAMPLE STORAGE AND SAMPLE MANAGEMENT FOR LIFE SCIENCE BIOMATRICA, INC. (US) 2009-03-26 WO claimed
US-20080176209-A1 INTEGRATION OF SAMPLE STORAGE AND SAMPLE MANAGEMENT FOR LIFE SCIENCE BIOMATRICA, INC. (US) 2008-07-24 US claimed
US-12637440-B2 Amide derivative useful as diacylglycerol acyltransferase 2 inhibitor, and use thereof LG CHEM, LTD. (KR) 2026-05-26 US disclosed
US-20260138987-A1 MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS CONTINEUM THERAPEUTICS INC (US) 2026-05-21 US disclosed
US-12630503-B2 Method for producing benzopyranone compound and novel intermediate used therein ILAB (KR) 2026-05-19 US disclosed
EP-4731623-A1 CARBOLINE COMPOUNDS AND USE THEREOF PTC Therapeutics, Inc. (US) 2026-04-29 EP disclosed
US-12565501-B2 Muscarinic acetylcholine M1 receptor antagonists CONTINEUM THERAPEUTICS, INC. (US) 2026-03-03 US disclosed
US-12552783-B2 Modulators of proteolysis and associated methods of use ARVINAS OPERATIONS, INC. (US) 2026-02-17 US disclosed
EP-0174858-A1 Isoindolinone derivatives, production and use thereof Takeda Chemical Industries, Ltd. (JP) 1986-03-19 EP disclosed
US-4528282-A Amide derivatives IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) 1985-07-09 US disclosed
US-4489093-A Insecticidal esters ROUSSEL UCLAF (FR) 1984-12-18 US disclosed
EP-0111105-A2 Unsaturated aromatic amides as pesticides THE WELLCOME FOUNDATION LIMITED (GB) 1984-06-20 EP disclosed
EP-0084941-A1 Amide derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-08-03 EP disclosed
EP-0070204-A2 Carboxylic beta-lactam compounds and the preparation thereof SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) 1983-01-19 EP disclosed
US-4065620-A ANTIBIOTICS ELI LILLY AND COMPANY (US) 1977-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12630503-B2 Method for producing benzopyranone compound and novel intermediate used therein TNF, NFKBIA, TNFRSF1A HSP90AA1 932/4885TSHR 1818/4885ALDH1A1 524/4885
US-12565501-B2 Muscarinic acetylcholine M1 receptor antagonists CHRM1, CHRM2, CHRM3 HSP90AA1 3500/4885TSHR 52/4885ALDH1A1 1427/4885
US-20260138987-A1 MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS CHRM1, CHRM5, CHRM3 HSP90AA1 3805/4885TSHR 71/4885ALDH1A1 1512/4885
US-20080176209-A1 INTEGRATION OF SAMPLE STORAGE AND SAMPLE MANAGEMENT FOR LIFE SCIENCE NEFM, DNASE1, DCTD HSP90AA1 856/4885TSHR 3097/4885ALDH1A1 2900/4885
US-12552783-B2 Modulators of proteolysis and associated methods of use CRBN, ADRM1, MDM2 HSP90AA1 1854/4885TSHR 2253/4885ALDH1A1 3965/4885
US-12637440-B2 Amide derivative useful as diacylglycerol acyltransferase 2 inhibitor, and use thereof DGAT2, DGAT1, DLAT HSP90AA1 1698/4885TSHR 2348/4885ALDH1A1 885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.