Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 5/20 | 0.49 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14884184 | 0.87 | ALDH1A1 (0.41) | LPLLIPGALDH1A1MAPTALPL | |
| SCHEMBL14884188 | 0.87 | ALDH1A1 (0.41) | LPLLIPGALDH1A1MAPTALPL | |
| SCHEMBL2268694 | 0.85 | LPL (0.45) | LPLLIPGALDH1A1GLAMAPT | |
| SCHEMBL29781408 | 0.85 | LPL (0.45) | LPLLIPGALDH1A1GLAMAPT | |
| SCHEMBL14884187 | 0.82 | ALDH1A1 (0.39) | LPLLIPGALDH1A1MAPTALPL | |
| SCHEMBL14884185 | 0.82 | ALDH1A1 (0.39) | LPLLIPGALDH1A1MAPTALPL | |
| SCHEMBL29254215 | 0.79 | LIPG (0.55) | LPLLIPGSNCA | |
| SCHEMBL21215940 | 0.78 | LPL (0.50) | LPLLIPGALDH1A1GLAMAPT | |
| SCHEMBL21215960 | 0.77 | LPL (0.52) | LPLLIPGALDH1A1MAPTALPL | |
| SCHEMBL21215967 | 0.77 | LPL (0.52) | LPLLIPGALDH1A1MAPTALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007086-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2012-01-19 | — | — | WO | disclosed |