SCHEMBL703499

SCHEMBL703499

CCCC(CCC)(CCC)C(=O)O[SiH3]

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.39
CYP4A11 Q02928 2/20 0.39
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ELANE P08246 1/20 0.32
THRB P10828 1/20 0.31
PKM P14618 1/20 0.31
FDPS P14324 2/20 0.31
HTT P42858 1/20 0.31
CES2 O00748 1/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7758101 0.93 CYP4F2 (0.42) CYP4F2CYP4A11LMNAHSD17B10MEN1
SCHEMBL2065097 0.86 CYP4F2 (0.46) CYP4F2CYP4A11MEN1MAPTKMT2A
SCHEMBL703088 0.86 CYP4F2 (0.46) CYP4F2CYP4A11MEN1MAPTKMT2A
SCHEMBL167166 0.81 CYP4F2 (0.43) CYP4F2CYP4A11THRBPKMALDH1A1
SCHEMBL7758102 0.78 LMNA (0.38) CYP4F2CYP4A11LMNAHSD17B10MEN1
SCHEMBL9141375 0.77 DGAT1 (0.36) CYP4F2CYP4A11LMNAHSD17B10MEN1
SCHEMBL6437220 0.75 LMNA (0.34) CYP4F2CYP4A11LMNAHSD17B10ELANE
SCHEMBL30608259 0.75 CYP4F2 (0.53) CYP4F2CYP4A11LMNAHSD17B10MEN1
SCHEMBL6437216 0.75 LMNA (0.34) CYP4F2CYP4A11LMNAHSD17B10ELANE
SCHEMBL9141368 0.75 LMNA (0.34) CYP4F2CYP4A11LMNAHSD17B10ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8148446-B2 Silyl esters, their use in binder systems and paint compositions and a process of production thereof SIGMAKALON B.V. (NL) 2012-04-03 US claimed
US-20100249298-A1 Silyl esters, their use in binder systems and paint compositions and a process of production thereof GILLARD MICHEL 2010-09-30 US claimed
EP-1620514-A2 SILYL ESTERS, THEIR USE IN BINDER SYSTEMS AND PAINT COMPOSITIONS AND A PROCESS OF PRODUCTION THEREOF SigmaKalon B.V. (NL) 2006-02-01 EP claimed
WO-2004099326-A2 SILYL ESTERS, THEIR USE IN BINDER SYSTEMS AND PAINT COMPOSITIONS AND A PROCESS OF PRODUCTION THEREOF SIGMAKALON B.V. (NL) 2004-11-18 WO claimed
US-8148446-B2 Silyl esters, their use in binder systems and paint compositions and a process of production thereof SIGMAKALON B.V. (NL) 2012-04-03 US disclosed
US-8124239-B2 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2012-02-28 US disclosed
US-20100249298-A1 Silyl esters, their use in binder systems and paint compositions and a process of production thereof GILLARD MICHEL 2010-09-30 US disclosed
US-20100155121-A1 SILICA FILM FORMING MATERIAL, SILICA FILM AND METHOD OF MANUFACTURING THE SAME, MULTILAYER WIRING STRUCTURE AND METHOD OF MANUFACTURING THE SAME, AND SEMICONDUCTOR DEVICE AND METHOD OF MANUFACTURING THE SAME FUJITSU LIMITED (JP) 2010-06-24 US disclosed
US-7659357-B2 Precursor organosilicon polymer of 1,2-Bis(dimethylethoxysilyl)ethane, 1,4-bis(dimethylethoxysilyl)benzene, tetraethoxysilane, methyltriethoxysilane, phenyltriethoxysilane; dielectric (DE) films having etching/chemical/moisture resistance; adhesion; low DE constant; minimal wiring delay; high speed FUJITSU LIMITED (JP) 2010-02-09 US disclosed
US-20090061633-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2009-03-05 US disclosed
US-20070026689-A1 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2007-02-01 US disclosed
US-7005398-B2 Olefin polymerization catalyst, catalyst component for olefin polymerization, method of storing these, and process for producing olefin polymer SUNALLOMER LTD. (JP) 2006-02-28 US disclosed
EP-1620514-A2 SILYL ESTERS, THEIR USE IN BINDER SYSTEMS AND PAINT COMPOSITIONS AND A PROCESS OF PRODUCTION THEREOF SigmaKalon B.V. (NL) 2006-02-01 EP disclosed
US-20050118742-A1 Method for reducing the adhesive properties of MEMS and anti-adhesion-coated device ROBERT BOSCH GMBH (DE) 2005-06-02 US disclosed
WO-2004099326-A2 SILYL ESTERS, THEIR USE IN BINDER SYSTEMS AND PAINT COMPOSITIONS AND A PROCESS OF PRODUCTION THEREOF SIGMAKALON B.V. (NL) 2004-11-18 WO disclosed
US-20040054102-A1 Olefin polymerization catalyst, catalyst component for olefin polymerization, method of storing these, and process for producing olefin polymer SUNALLOMER LTD. (JP) 2004-03-18 US disclosed
EP-1359166-A1 OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, METHOD OF STORING THESE, AND PROCESS FOR PRODUCING OLEFIN POLYMER Sunallomer Ltd (JP) 2003-11-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249298-A1 Silyl esters, their use in binder systems and paint compositions and a process of production thereof LCT, PCMT1, TST CYP4F2 1316/4885CYP4A11 672/4885LMNA 3691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.