SCHEMBL360859

SCHEMBL360859

[c]1ccccc1-c1ccc(Oc2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 8/20 0.48
TSHR P16473 1/20 0.48
GSTP1 P09211 1/20 0.46
NR1H2 P55055 1/20 0.43
BAX Q07812 1/20 0.43
MAOA P21397 1/20 0.43
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
SCN4A P35499 1/20 0.41
TLR8 Q9NR97 1/20 0.40
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
MGLL Q99685 1/20 0.39
NISCH Q9Y2I1 1/20 0.39
RIPK1 Q13546 1/20 0.37
SOS1 Q07889 1/20 0.37
CA9 Q16790 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6131987 0.83 MAOB (0.44) LTA4HTSHRGSTP1
SCHEMBL27553954 0.81 MAOB (0.49) GSTP1MAOA
SCHEMBL8529939 0.81 GSTP1 (0.47) LTA4HTSHRGSTP1NR1H2BAX
SCHEMBL769959 0.81 ALDH1A1 (0.45) CA1CA2MGLLCA9
SCHEMBL769634 0.81 ALDH1A1 (0.45) CA1CA2MGLLCA9
SCHEMBL25097 0.81 ALDH1A1 (0.45) CA1CA2MGLLCA9
SCHEMBL38202 0.80 ALDH1A1 (0.42) NPC1RAB9A
SCHEMBL41140 0.80 ALDH1A1 (0.42) NPC1RAB9A
SCHEMBL592654 0.80 CA4 (0.44) LTA4HNPC1RAB9ACA1CA2
SCHEMBL27574720 0.80 FFAR1 (0.39) GSTP1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3880474-A1 PLASTIC FILMS HAVING HIGH OPACITY AND LOW TRANSPARENCY FOR ID DOCUMENTS HAVING A TRANSPARENT WINDOW Covestro Intellectual Property GmbH & Co. KG (DE) 2021-09-22 EP disclosed
EP-3840958-A1 IMPROVED METHOD FOR THE PARTIAL COLORING OF PLASTIC PARTS Covestro Intellectual Property GmbH & Co. KG (DE) 2021-06-30 EP disclosed
EP-3727851-A1 PLASTIC FILMS FOR ID DOCUMENTS WITH BETTER LIGHTNESS OF EMBOSSED HOLOGRAMS Covestro Deutschland AG (DE) 2020-10-28 EP disclosed
EP-3721292-A1 ADHESIVE-FREE PHOTOPOLYMER LAYER STRUCTURE Covestro Deutschland AG (DE) 2020-10-14 EP disclosed
WO-2020099344-A1 PLASTIC FILMS HAVING HIGH OPACITY AND LOW TRANSPARENCY FOR ID DOCUMENTS HAVING A TRANSPARENT WINDOW COVESTRO DEUTSCHLAND AG (DE) 2020-05-22 WO disclosed
EP-3645297-A1 IMPROVED METHOD FOR THE PARTIAL COLOURING OF PLASTIC PARTS Covestro Deutschland AG (DE) 2020-05-06 EP disclosed
EP-3630875-A1 FILMS HAVING A SCRATCH-RESISTANT COATING AS A COVER LAYER AND LAYERED COMPOSITES COMPRISING SUCH FILMS Covestro Deutschland AG (DE) 2020-04-08 EP disclosed
WO-2020039018-A1 IMPROVED METHOD FOR THE PARTIAL COLORING OF PLASTIC PARTS COVESTRO DEUTSCHLAND AG (DE) 2020-02-27 WO disclosed
WO-2019110505-A1 ADHESIVE-FREE PHOTOPOLYMER LAYER STRUCTURE COVESTRO DEUTSCHLAND AG (DE) 2019-06-13 WO disclosed
EP-3436284-A1 METHOD FOR THE PARTIAL COLORING OF PLASTIC PARTS Covestro Deutschland AG (DE) 2019-02-06 EP disclosed
EP-2197656-A2 METHOD FOR PRODUCING A DEEP-DRAWN FILM PART FROM A THERMOPLASTIC MATERIAL Bayer MaterialScience AG (DE) 2010-06-23 EP disclosed
WO-2010034407-A1 FORGERY-PROOF SECURITY FEATURES IN SECURITY OR VALUE DOCUMENTS BAYER MATERIALSCIENCE AG (DE) 2010-04-01 WO disclosed
WO-2010034409-A1 USE OF A PLASTIC FILM IN COLOUR LASER PRINTING BAYER MATERIALSCIENCE AG (DE) 2010-04-01 WO disclosed
WO-2009078932-A1 3,4-SUBSTITUTED PYRROLIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE MERCK & CO., INC. (US) 2009-06-25 WO disclosed
WO-2009043539-A2 METHOD FOR PRODUCING A DEEP-DRAWN FILM PART FROM A THERMOPLASTIC MATERIAL BAYER MATERIALSCIENCE AG (DE) 2009-04-09 WO disclosed
US-20090039313-A1 (Thio)phenoxy phenyl silane compostion and method for making same ROHM AND HAAS COMPANY (US) 2009-02-12 US disclosed
EP-2019106-A1 (Thio)Phenoxy Phenyl Silane Composition And Method For Making Same Rohm and Haas Company (US) 2009-01-28 EP disclosed
WO-2006118749-A1 THIA-TETRAAZAACENAPHTHYLENE KINASE INHIBITORS JANSSEN PHARMACEUTICA, N.V. (BE) 2006-11-09 WO disclosed
EP-1216285-A1 FLUORESCENT MALEIMIDES AND USES THEREOF Ciba SC Holding AG (CH) 2002-06-26 EP disclosed
WO-2001019939-A1 FLUORESCENT MALEIMIDES AND USES THEREOF CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090039313-A1 (Thio)phenoxy phenyl silane compostion and method for making same TPMT, TTR, TST LTA4H 671/4885TSHR 3707/4885GSTP1 95/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.