Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 12/20 | 0.39 |
| ▸ | RARB | P10826 | 7/20 | 0.39 |
| ▸ | RARG | P13631 | 7/20 | 0.39 |
| ▸ | RARA | P10276 | 5/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 8/20 | 0.36 |
| ▸ | RXRB | P28702 | 7/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3609445 | 1.00 | RXRA (0.39) | RXRARARBRARGRARAESR1 | |
| Oxeglitazar SCHEMBL3605899 | 0.92 | RXRA (0.41) | RXRARARBRARGRARARXRG | |
| Oxeglitazar SCHEMBL1547425 | 0.92 | RXRA (0.41) | RXRARARBRARGRARARXRG | |
| Oxeglitazar SCHEMBL29372761 | 0.92 | RXRA (0.41) | RXRARARBRARGRARARXRG | |
| Oxeglitazar SCHEMBL1547427 | 0.92 | RXRA (0.41) | RXRARARBRARGRARARXRG | |
| SCHEMBL2315833 | 0.88 | ESR1 (0.38) | ESR1ESR2CYP19A1ALDH1A1MAPT | |
| SCHEMBL2315836 | 0.88 | ESR1 (0.38) | ESR1ESR2CYP19A1ALDH1A1MAPT | |
| SCHEMBL3646386 | 0.87 | MAPT (0.36) | ESR1ESR2ALDH1A1MAPTKDM4E | |
| SCHEMBL3646383 | 0.87 | MAPT (0.36) | ESR1ESR2ALDH1A1MAPTKDM4E | |
| SCHEMBL3600980 | 0.86 | RXRA (0.39) | RXRARARBRARGRARAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160410-A1 | USE OF PENTADIENOIC ACID DERIVATIVES FOR THE TREATMENT OF HYPERURICEMIA | BOIZEL ROBERT | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160410-A1 | USE OF PENTADIENOIC ACID DERIVATIVES FOR THE TREATMENT OF HYPERURICEMIA | XDH, URB2, ALOX12 | RXRA 61/4885RARB 354/4885RARG 405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.