Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.58 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.58 |
| ▸ | HTR1B | P28222 | 2/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 5/20 | 0.46 |
| ▸ | WNT3A | P56704 | 5/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.43 |
| ▸ | HTR3A | P46098 | 3/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | GRN | P28799 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2821662 | 0.78 | TAS1R3 (0.60) | TAS1R3TAS1R1HTR1BCTNNB1WNT3A | |
| SCHEMBL27601966 | 0.77 | TAS1R3 (0.65) | TAS1R3TAS1R1HTR1BCTNNB1WNT3A | |
| SCHEMBL12020481 | 0.75 | HTR1B (0.63) | TAS1R3TAS1R1HTR1BCTNNB1WNT3A | |
| SCHEMBL702813 | 0.75 | TAS1R3 (0.59) | TAS1R3TAS1R1HTR1B | |
| SCHEMBL29169869 | 0.75 | HTR1B (0.67) | TAS1R3TAS1R1HTR1BCTNNB1WNT3A | |
| SCHEMBL2408440 | 0.74 | TAS1R3 (0.56) | TAS1R3TAS1R1HTR1BCTNNB1WNT3A | |
| Hydrochloric Acid SCHEMBL30164255 | 0.74 | HTR1B (0.61) | TAS1R3TAS1R1HTR1BCTNNB1WNT3A | |
| SCHEMBL14880251 | 0.74 | HTR1B (0.56) | TAS1R3TAS1R1HTR1BCTNNB1WNT3A | |
| SCHEMBL10226453 | 0.73 | TAS1R3 (1.00) | TAS1R3TAS1R1 | |
| SCHEMBL2405242 | 0.73 | HDAC1 (0.60) | TAS1R3TAS1R1HTR1BCTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100256165-A1 | LARGE CONDUCTANCE CALCIUM-ACTIVATED K CHANNEL OPENER | HONGU MITSUYA | 2010-10-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100256165-A1 | LARGE CONDUCTANCE CALCIUM-ACTIVATED K CHANNEL OPENER | KCNN3, KCNN2, KCNN1 | TAS1R3 868/4885TAS1R1 975/4885HTR1B 2649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.