Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trimethylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6142288 | 0.92 | THRB (0.42) | THRBTSHRALDH1A1GLO1LMNA | |
| Sulfuric Acid SCHEMBL631032 | 0.91 | THRB (0.50) | THRBTSHRALDH1A1GLO1LMNA | |
| Sulfuric Acid Dimethyl Ester SCHEMBL27602576 | 0.89 | THRB (0.46) | THRBTSHRALDH1A1GLO1LMNA | |
| Trimethylammonium SCHEMBL25283249 | 0.89 | THRB (0.48) | THRBTSHRALDH1A1GLO1LMNA | |
| SCHEMBL28478533 | 0.88 | THRB (0.46) | THRBTSHRALDH1A1GLO1GAA | |
| Trimethylammonium SCHEMBL421649 | 0.87 | THRB (0.57) | THRBTSHRALDH1A1GLO1LMNA | |
| Trimethylammonium SCHEMBL4974909 | 0.86 | TSHR (0.50) | THRBTSHRALDH1A1 | |
| SCHEMBL28478534 | 0.85 | TSHR (0.39) | THRBTSHRALDH1A1CYP2D6CYP2C19 | |
| Sulfuric Acid SCHEMBL1169601 | 0.85 | THRB (0.55) | THRBTSHRALDH1A1GLO1LMNA | |
| Trimethylammonium SCHEMBL7150631 | 0.85 | THRB (0.55) | THRBTSHRALDH1A1GLO1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2209824-B1 | HIGH DEFINITION PRINTING WITH WATERBORNE INKS ON NON-POROUS SUBSTRATES | RHODIA (US) | 2012-08-08 | — | — | EP | claimed |
| US-8025918-B2 | High definition printing with waterborne inks on non-porous substrates | RHODIA, INC. (US) | 2011-09-27 | — | — | US | claimed |
| EP-2209824-A2 | HIGH DEFINITION PRINTING WITH WATERBORNE INKS ON NON-POROUS SUBSTRATES | Rhodia, Inc. (US) | 2010-07-28 | — | — | EP | claimed |
| WO-2009065004-A2 | HIGH DEFINITION PRINTING WITH WATERBORNE INKS ON NON-POROUS SUBSTRATES | RHODIA, INC. (US) | 2009-05-22 | — | — | WO | claimed |
| US-20090130295-A1 | High Definition Printing With Waterborne Inks on Non-Porous Substrates | RHODIA OPERATIONS (FR) | 2009-05-21 | — | — | US | claimed |
| EP-2136999-B1 | INK-JET RECORDING METHOD | RICOH CO LTD (JP) | 2015-02-25 | — | — | EP | disclosed |
| EP-2183117-B1 | INKJET MEDIUM AND INKJET RECORDING METHOD | RICOH CO LTD (JP) | 2014-10-01 | — | — | EP | disclosed |
| US-8425031-B2 | Inkjet medium, ink and inkjet recording method | RICOH COMPANY, LTD. (JP) | 2013-04-23 | — | — | US | disclosed |
| EP-2200836-B1 | INKJET RECORDING METHOD AND MEDIUM | RICOH CO LTD (JP) | 2012-12-26 | — | — | EP | disclosed |
| US-8322839-B2 | Inkjet recording method, inkjet recording medium, and aqueous ink | RICOH COMPANY, LTD. (JP) | 2012-12-04 | — | — | US | disclosed |
| EP-2209824-B1 | HIGH DEFINITION PRINTING WITH WATERBORNE INKS ON NON-POROUS SUBSTRATES | RHODIA (US) | 2012-08-08 | — | — | EP | disclosed |
| US-8096651-B2 | Ink-jet recording method, ink, ink cartridge, recording apparatus, and recorded matter | RICOH COMPANY, LTD. (JP) | 2012-01-17 | — | — | US | disclosed |
| EP-2183117-A1 | INKJET MEDIUM, INK AND INKJET RECORDING METHOD | Ricoh Company, Ltd. (JP) | 2010-05-12 | — | — | EP | disclosed |
| WO-2009116678-A1 | INKJET RECORDING METHOD, INKJET RECORDING MEDIUM, AND AQUEOUS INK | RICOH COMPANY, LTD. (JP) | 2009-09-24 | — | — | WO | disclosed |
| WO-2009065004-A2 | HIGH DEFINITION PRINTING WITH WATERBORNE INKS ON NON-POROUS SUBSTRATES | RHODIA, INC. (US) | 2009-05-22 | — | — | WO | disclosed |
| US-20090130295-A1 | High Definition Printing With Waterborne Inks on Non-Porous Substrates | RHODIA OPERATIONS (FR) | 2009-05-21 | — | — | US | disclosed |
| WO-2009028733-A1 | INKJET MEDIUM, INK AND INKJET RECORDING METHOD | RICOH COMPANY, LTD. (JP) | 2009-03-05 | — | — | WO | disclosed |
| WO-2008114884-A1 | INK-JET RECORDING METHOD, INK, INK CARTRIDGE, RECORDING APPARATUS, AND RECORDED MATTER | RICOH COMPANY, LTD. (JP) | 2008-09-25 | — | — | WO | disclosed |
| US-4215162-A | Process of coating metal surfaces | AKZO N.V. (NL) | 1980-07-29 | — | — | US | disclosed |
| US-4214022-A | CATIONIC SURFACTANT, CARBOXYLIC ACID WHICH COMPLEXES WITH METAL IONS FORMED BY ETCHING | AKZO N.V. (NL) | 1980-07-22 | — | — | US | disclosed |