Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | TSPO | P30536 | 4/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29873867 | 0.75 | CYP17A1 (0.51) | GAAKMT2A | |
| SCHEMBL13548240 | 0.75 | CYP17A1 (0.51) | GAAKMT2A | |
| SCHEMBL4065895 | 0.75 | KDM4C (0.34) | GAAKMT2AALDH1A1KDM4CKDM4E | |
| SCHEMBL2511336 | 0.74 | LMNA (0.62) | LMNAGAAKMT2AALDH1A1CYP1A2 | |
| SCHEMBL4072497 | 0.72 | KDM4C (0.34) | LMNAGAAKMT2AALDH1A1KDM4C | |
| SCHEMBL15787106 | 0.72 | CA12 (0.56) | LMNAGAAKMT2AALDH1A1CYP1A2 | |
| SCHEMBL3831425 | 0.71 | CHRM5 (0.41) | LMNAGAAKMT2AKDM4E | |
| Acetic Acid SCHEMBL16021009 | 0.69 | KDM4C (0.32) | KMT2AALDH1A1KDM4CKDM4ECCNC | |
| SCHEMBL3503371 | 0.68 | CYP2A6 (0.48) | LMNAGAAKMT2AALDH1A1HSD17B10 | |
| SCHEMBL2117365 | 0.68 | SMN1; SMN2 (0.47) | GAAKMT2AALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100016307-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016307-A1 | NOVEL COMPOUNDS | MET, HGF, HGFAC | LMNA 2906/4885GAA 1163/4885KMT2A 3746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.