Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | MTHFD1 | P11586 | 2/20 | 0.71 |
| ▸ | SOST | Q9BQB4 | 1/20 | 0.67 |
| ▸ | MTHFD2 | P13995 | 2/20 | 0.62 |
| ▸ | FPGS | Q05932 | 2/20 | 0.60 |
| ▸ | TYMS | P04818 | 1/20 | 0.55 |
| ▸ | GART | P22102 | 5/20 | 0.55 |
| ▸ | ATIC | P31939 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Leucovorin SCHEMBL159828 | 1.00 | DHFR (1.00) | DHFRLMNAMTHFD1SOSTMTHFD2 | |
| Leucovorin SCHEMBL4575698 | 1.00 | DHFR (1.00) | DHFRLMNAMTHFD1SOSTMTHFD2 | |
| Leucovorin SCHEMBL258832 | 1.00 | DHFR (1.00) | DHFRLMNAMTHFD1SOSTMTHFD2 | |
| Levoleucovorin SCHEMBL639769 | 1.00 | DHFR (1.00) | DHFRLMNAMTHFD1SOSTMTHFD2 | |
| Leucovorin SCHEMBL3031362 | 1.00 | DHFR (1.00) | DHFRLMNAMTHFD1SOSTMTHFD2 | |
| Folinic Acid SCHEMBL29616563 | 1.00 | DHFR (1.00) | DHFRLMNAMTHFD1SOSTMTHFD2 | |
| Leucovorin SCHEMBL29385578 | 1.00 | DHFR (1.00) | DHFRLMNAMTHFD1SOSTMTHFD2 | |
| Leucovorin SCHEMBL29379632 | 1.00 | DHFR (1.00) | DHFRLMNAMTHFD1SOSTMTHFD2 | |
| Folinic Acid SCHEMBL21498299 | 1.00 | DHFR (1.00) | DHFRLMNAMTHFD1SOSTMTHFD2 | |
| Leucovorin SCHEMBL4744838 | 0.99 | DHFR (0.98) | DHFRLMNAMTHFD1SOSTMTHFD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 34261 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746876-A1 | UDP-GLUCOSE CERAMIDE GLUCOSYLTRANSFERASE SYNTHASE (UGCG) INHIBITORS IN THE TREATMENT OF CANCER | Katholieke Universiteit Leuven (BE) | 2026-05-27 | — | — | EP | claimed |
| CN-122094686-A | Oncolytic adenovirus and topoisomerase I inhibitors for the treatment of cancer | — | 2026-05-26 | — | — | CN | claimed |
| CN-122075411-A | Tripterine liposome, its combined medicine and its application in preventing and treating tumor | — | 2026-05-26 | — | — | CN | claimed |
| CN-122074090-A | Diversified phage synthesis and engineering platform | 修兰教育基金管理公司 | 2026-05-22 | — | — | CN | claimed |
| CN-122074048-A | Methods of treating cancer | 诺华股份有限公司 | 2026-05-22 | — | — | CN | claimed |
| US-20260137678-A1 | METHODS FOR TREATING OR PREVENTING NEUROENDOCRINE TUMOR FORMATION USING XPO1 INHIBITORS | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2026-05-21 | — | — | US | claimed |
| EP-3841097-B1 | 2,6-BIS(((1H-BENZO[D]IMIDAZOL-2-YL)THIO)METHYL)PYRIDINE AND N2,N6-DIBENZYLPYRIDINE-2,6-DICARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS PHOSPHOINOSITIDE 3-KINASE (PI3K) INHIBITORS FOR TREATING CANCER | BIOMEDICAL RES FOUNDATION OF THE ACADEMY OF ATHENS BRFAA (GR) | 2026-05-20 | — | — | EP | claimed |
| EP-4743490-A1 | HUMANIZED ANTI-CD7 ANTIBODY | Christian-Albrechts-Universität zu Kiel (DE) | 2026-05-20 | — | — | EP | claimed |
| WO-2026099502-A1 | NOVEL DRUG CONJUGATES FOR TESTING CELLULAR DRUG UPTAKE | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2026-05-15 | — | — | WO | claimed |
| US-20260130855-A1 | GAMMA POLYGLUTAMATED ANTIFOLATES AND USES THEREOF | L E A F HOLDINGS GROUP LLC (US) | 2026-05-14 | — | — | US | claimed |
| CN-88102709-A | Method for separating folinic acid | — | 1988-12-28 | — | — | CN | claimed |
| WO-1988008844-A1 | PROCESS FOR SEPARATION OF FOLINIC ACIDS | EPROVA AG (CH) | 1988-11-17 | — | — | WO | claimed |
| EP-0266042-A2 | Optically active pteridine derivatives | University of Strathclyde (GB) | 1988-05-04 | — | — | EP | claimed |
| EP-0096560-B1 | ASSESSMENT OF NUTRITIONAL STATUS OF INDIVIDUALS | Clayton Foundation for Research (US) | 1987-05-06 | — | — | EP | claimed |
| US-4533637-A | REPLACING SERUM WITH CYCLODEXTRINS | AJINOMOTO CO., INC. (JP) | 1985-08-06 | — | — | US | claimed |
| US-4499064-A | Assessment of nutritional status of individuals | CLAYTON FOUNDATION FOR RESEARCH (US) | 1985-02-12 | — | — | US | claimed |
| EP-0121399-A2 | A method for producing hybrids between myeloma cells and normal cells | BIO-RESPONSE INC. (US) | 1984-10-10 | — | — | EP | claimed |
| EP-0096560-A1 | Assessment of nutritional status of individuals | Clayton Foundation for Research (US) | 1983-12-21 | — | — | EP | claimed |
| US-4383845-A | Foliar growth promoting mixture | RUTHERFORD JOSEPH P | 1983-05-17 | — | — | US | claimed |
| EP-0051278-A1 | Soft tertiary amine esters of bio-affecting carboxylic acids, processes for preparing and a pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1982-05-12 | — | — | EP | claimed |