Bisphenol A

Bisphenol A

SCHEMBL7055236

CC(C)(c1ccc(O)cc1)c1ccc(O)cc1.O=C(O)c1ccc(C(=O)Oc2ccc(O)cc2)cc1.O=C(O)c1cccc(C(=O)O)c1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
ESR1 P03372 3/20 0.45
ESR2 Q92731 3/20 0.45
PARP10 Q53GL7 1/20 0.44
NR4A2 P43354 2/20 0.44
NR4A1 P22736 1/20 0.44
NR4A3 Q92570 1/20 0.44
NPC1 O15118 1/20 0.44
POLB P06746 1/20 0.44
CYP2C9 P11712 1/20 0.44
RAB9A P51151 1/20 0.44
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
ALDH1A1 P00352 3/20 0.44
CYP3A4 P08684 1/20 0.44
ELANE P08246 2/20 0.43
RXRA P19793 2/20 0.43
RXRB P28702 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isophthalic Acid SCHEMBL1410762 1.00 MAPT (0.56) MAPTTDP1L3MBTL1ESR1ESR2
Terephthalic Acid SCHEMBL361198 0.97 MAPT (0.52) MAPTTDP1L3MBTL1ESR1ESR2
SCHEMBL4859006 0.95 MAPT (0.55) MAPTTDP1L3MBTL1ESR1ESR2
SCHEMBL9246472 0.93 MAPT (0.60) MAPTTDP1L3MBTL1ESR1ESR2
Bisphenol A SCHEMBL6678074 0.93 KMT2A (0.50) MAPTTDP1L3MBTL1ESR1ESR2
Bisphenol A SCHEMBL7535174 0.93 KMT2A (0.50) MAPTTDP1L3MBTL1ESR1ESR2
Bicarbonate SCHEMBL9249849 0.92 MAPT (0.58) MAPTTDP1L3MBTL1ESR1ESR2
SCHEMBL2854092 0.92 MAPT (0.56) MAPTTDP1L3MBTL1ESR1ESR2
SCHEMBL10875111 0.89 MAPT (0.56) MAPTTDP1L3MBTL1ESR1ESR2
SCHEMBL12451793 0.89 MAPT (0.69) MAPTTDP1L3MBTL1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1115792-B1 WEATHERABLE BLENDS OF POLYCARBONATES WITH ARYLATE POLYMERS GEN ELECTRIC (US) 2003-04-23 EP disclosed
EP-1115792-A1 WEATHERABLE BLENDS OF POLYCARBONATES WITH ARYLATE POLYMERS GENERAL ELECTRIC COMPANY (US) 2001-07-18 EP disclosed
US-6143839-A THERMOPLASTIC ARYLATE POLYMER COMPRISING UNITS DERIVED FROM A RESORCINOL OR ALKYLRESORCINOL ISOPHTHALATE-TEREPHTHALATE IMPROVES COLOR STABILITY OR GLOSS RETENTION OF THE POLYCARBONATE; ARTICLES MADE FROM THE BLEND GENERAL ELECTRIC COMPANY (US) 2000-11-07 US disclosed
WO-2000015718-A1 WEATHERABLE BLENDS OF POLYCARBONATES WITH ARYLATE POLYMERS GENERAL ELECTRIC COMPANY (US) 2000-03-23 WO disclosed