Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 2/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.40 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3602192 | 0.86 | CAMK2D (0.58) | CCNT1CAMK2DCSNK2A1EIF2AK2KDM4E | |
| SCHEMBL3612021 | 0.80 | SYK (0.43) | SYKDYRK1ACLK4DYRK1BCAMK2D | |
| SCHEMBL3610719 | 0.79 | CAMK2D (0.54) | CCNT1CAMK2DCSNK2A1EIF2AK2KDM4E | |
| SCHEMBL3617505 | 0.77 | MAPT (0.53) | CCNT1CAMK2DCSNK2A1EIF2AK2KDM4E | |
| SCHEMBL3609046 | 0.77 | CDK1 (0.65) | CCNT1CAMK2DCSNK2A1EIF2AK2KDM4E | |
| SCHEMBL3609491 | 0.76 | CAMK2D (0.53) | CCNT1CAMK2DCSNK2A1EIF2AK2KDM4E | |
| SCHEMBL3608870 | 0.76 | CAMK2D (0.57) | CCNT1CAMK2DCSNK2A1EIF2AK2KDM4E | |
| SCHEMBL3597064 | 0.75 | PIK3CA (0.52) | CCNT1CAMK2DCSNK2A1EIF2AK2KDM4E | |
| SCHEMBL3603990 | 0.74 | CAMK2D (0.60) | CCNT1SYKCAMK2DCSNK2A1KDM4E | |
| SCHEMBL3605169 | 0.73 | CDK2 (0.51) | CCNT1CAMK2DCSNK2A1EIF2AK2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048597-A1 | Organic Compounds and Their Uses | NOVARTIS AG | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048597-A1 | Organic Compounds and Their Uses | OAT, OTC, AOX1 | FLT3 4558/4885CCNT1 3196/4885SYK 2976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.