Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.44 |
| ▸ | WNT1 | P04628 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3600659 | 0.99 | PTGER1 (0.48) | PTGER1SMN1; SMN2SLC2A1WNT1GSK3B | |
| SCHEMBL3604806 | 0.93 | PTGER1 (0.49) | PTGER1SMN1; SMN2SLC2A1WNT1GSK3B | |
| Hydrochloric Acid SCHEMBL3607482 | 0.92 | PTGER1 (0.49) | PTGER1SMN1; SMN2SLC2A1WNT1GSK3B | |
| SCHEMBL13504910 | 0.89 | SLC2A1 (0.48) | PTGER1SMN1; SMN2SLC2A1WNT1GSK3B | |
| Hydrochloric Acid SCHEMBL3600084 | 0.88 | SLC2A1 (0.50) | PTGER1SMN1; SMN2SLC2A1WNT1GSK3B | |
| Hydrochloric Acid SCHEMBL3604615 | 0.86 | SMN1; SMN2 (0.49) | PTGER1SMN1; SMN2SLC2A1WNT1GSK3B | |
| SCHEMBL3606877 | 0.86 | ALDH1A1 (0.47) | PTGER1SMN1; SMN2SLC2A1WNT1GSK3B | |
| Hydrochloric Acid SCHEMBL3611595 | 0.86 | ALDH1A1 (0.46) | PTGER1SMN1; SMN2SLC2A1WNT1GSK3B | |
| SCHEMBL3608032 | 0.85 | MEN1 (0.55) | PTGER1SMN1; SMN2SLC2A1WNT1GSK3B | |
| SCHEMBL3602522 | 0.83 | SMN1; SMN2 (0.60) | PTGER1SMN1; SMN2SLC2A1WNT1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041696-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION | 2010-02-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041696-A1 | Compounds | CYP11B2, SCD, CYP3A5 | PTGER1 727/4885SMN1; SMN2 618/4885SLC2A1 1415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.