SCHEMBL3612896

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5520687	0.85	MEN1 (0.50)	MEN1KMT2AMAPTPTPRCS100A4
	SCHEMBL4012160	0.85	MAPT (0.48)	MEN1KMT2AMAPTPTPRCS100A4
	SCHEMBL6281274	0.76	MEN1 (0.40)	MEN1KMT2AMAPTPTPRCS100A4
	SCHEMBL2567528	0.76	MEN1 (0.50)	MEN1KMT2AKDM4EALDH1A1TSHR
	SCHEMBL28354161	0.76	ALDH1A1 (0.33)	MEN1KMT2AMAPTPTPRCS100A4
	SCHEMBL5576916	0.76	MEN1 (0.50)	MEN1KMT2AKDM4EALDH1A1TSHR
	SCHEMBL9420922	0.76	ALDH1A1 (0.33)	MEN1KMT2AMAPTPTPRCS100A4
	SCHEMBL11120020	0.76	ADORA2A (0.53)	MEN1KMT2AMAPTPTPRCS100A4
	SCHEMBL11422595	0.76	DNMT1 (0.33)	MEN1KMT2AMAPTPTPRCS100A4
	SCHEMBL4508095	0.76	HDAC4 (0.45)	MAPTLMNAMAPK1KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.