SCHEMBL5576916

SCHEMBL5576916

N#Cc1cccc2c1-c1ccccc1-c1ccccc1-c1ccccc1-2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
PDK2 Q15119 1/20 0.47
USP8 P40818 1/20 0.45
USP7 Q93009 1/20 0.45
ESR2 Q92731 1/20 0.45
TSHR P16473 1/20 0.44
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
MCL1 Q07820 1/20 0.39
DRD2 P14416 1/20 0.37
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36
IMPDH2 P12268 2/20 0.35
IMPDH1 P20839 1/20 0.35
CYP1A2 P05177 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2567528 1.00 MEN1 (0.50) MEN1KMT2APDK2USP8USP7
SCHEMBL27909137 0.83 ESR2 (0.52) MEN1KMT2APDK2USP8USP7
SCHEMBL9266802 0.83 USP8 (0.58) MEN1KMT2APDK2USP8USP7
SCHEMBL9265082 0.83 USP8 (0.58) MEN1KMT2APDK2USP8USP7
SCHEMBL28930001 0.81 ALDH1A1 (0.50) MEN1KMT2APDK2USP8USP7
SCHEMBL31663516 0.81 ESR2 (0.47) MEN1KMT2APDK2USP8USP7
SCHEMBL27365154 0.81 ESR2 (0.47) MEN1KMT2APDK2USP8USP7
SCHEMBL25774474 0.81 ADORA2A (0.40) MEN1KMT2APDK2ESR2TSHR
SCHEMBL18411431 0.80 ESR2 (0.50) MEN1KMT2APDK2ESR2TSHR
SCHEMBL16656169 0.78 MEN1 (0.56) MEN1KMT2APDK2USP8USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11958825-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2024-04-16 US claimed
US-20230174502-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2023-06-08 US claimed
US-11608321-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-03-21 US claimed
US-20180370944-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-12-27 US claimed
US-11958825-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION 2024-04-16 US disclosed
US-20230174502-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2023-06-08 US disclosed
US-11608321-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-03-21 US disclosed
US-20180370944-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2018-12-27 US disclosed
EP-1835007-A2 Nanofibres from functionalised organic molecules Carl von Ossietzky Universität Oldenburg (DE) 2007-09-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11958825-B2 Organic electroluminescent materials and devices PAX2, PAX3, HPRT1 MEN1 3624/4885KMT2A 2715/4885PDK2 572/4885
US-11608321-B2 Organic electroluminescent materials and devices PAX2, PAX3, HPRT1 MEN1 3624/4885KMT2A 2715/4885PDK2 572/4885
US-20180370944-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PAX2, PAX3, HPRT1 MEN1 3473/4885KMT2A 2765/4885PDK2 578/4885
US-20230174502-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PAX2, PAX3, HPRT1 MEN1 3473/4885KMT2A 2765/4885PDK2 578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.