Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010562 | 0.93 | CA2 (0.35) | MEN1KMT2ACYP2D6CYP19A1CA2 | |
| SCHEMBL4011999 | 0.91 | CA2 (0.39) | MEN1KMT2ACA2CHKAKDM4E | |
| SCHEMBL2073215 | 0.87 | MAPT (0.35) | MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL5212672 | 0.85 | MAPT (0.34) | MEN1KMT2AKDM4E | |
| SCHEMBL27862956 | 0.75 | CYP2D6 (0.35) | MEN1KMT2ACYP2D6CYP19A1 | |
| SCHEMBL1821639 | 0.75 | MEN1 (0.33) | MEN1KMT2ACYP2D6CYP19A1OPRD1 | |
| SCHEMBL6398141 | 0.75 | MEN1 (0.33) | MEN1KMT2ACYP2D6CYP19A1 | |
| SCHEMBL1819138 | 0.75 | CHRM2 (0.34) | MEN1KMT2ACYP2D6CYP19A1OPRD1 | |
| SCHEMBL26091887 | 0.75 | FDPS (0.35) | — | |
| SCHEMBL15013158 | 0.74 | CYP19A1 (0.31) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097594-B2 | Macrolides and ketolides having antimicrobial activity | WOCKHARDT LTD. (IN) | 2012-01-17 | — | — | US | disclosed |