Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4010562 | 0.98 | CA2 (0.35) | CA2CHKAKDM4EUSP2SMN1; SMN2 | |
| SCHEMBL361322 | 0.91 | MEN1 (0.35) | CA2CHKAKDM4EMEN1KMT2A | |
| SCHEMBL4430883 | 0.86 | FDPS (0.39) | SMN1; SMN2LMNAMAPTHTTFDPS | |
| SCHEMBL26091887 | 0.83 | FDPS (0.35) | LMNAMAPTHTTFDPS | |
| SCHEMBL2073215 | 0.79 | MAPT (0.35) | KDM4EMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5212672 | 0.78 | MAPT (0.34) | KDM4EMAPTMEN1KMT2A | |
| SCHEMBL5201421 | 0.71 | — | — | |
| SCHEMBL4903200 | 0.70 | CA2 (0.38) | CA2CHKAKDM4EUSP2SMN1; SMN2 | |
| SCHEMBL28104226 | 0.70 | CA2 (0.38) | CA2CHKAKDM4EUSP2SMN1; SMN2 | |
| SCHEMBL2674403 | 0.70 | CA2 (0.38) | CA2CHKAKDM4EUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074083-A1 | NEW SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | Richter Gedeon NYRT (HU) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008050168-A1 | NEW SULFONAMIDE DERIVATIVES AS BRADYKININ ANTAGONISTS | RICHTER GEDEON NYRT. (HU) | 2008-05-02 | — | — | WO | disclosed |