SCHEMBL361360

SCHEMBL361360

C=CCNC(=S)SSC(N)=S

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
TSHR P16473 2/20 0.56
KDM4A O75164 1/20 0.38
KDM4E B2RXH2 1/20 0.37
MAPT P10636 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
MAPK1 P28482 1/20 0.33
GAA P10253 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20734581 0.89 ALDH1A1 (0.54) ALDH1A1TSHRKDM4AMAPTSMN1; SMN2
SCHEMBL4560331 0.88 ALDH1A1 (0.52) ALDH1A1TSHRKDM4AKDM4EMAPT
SCHEMBL20734640 0.79 KDM4A (0.67) ALDH1A1TSHRKDM4AMAPTSMN1; SMN2
SCHEMBL10488735 0.75 ALDH1A1 (0.45) ALDH1A1TSHRKDM4AMAPTSMN1; SMN2
SCHEMBL11855121 0.73
Allylthiourea SCHEMBL29372 0.72
SCHEMBL3685999 0.71 KDM4A (0.76) ALDH1A1KDM4AMAPTGAA
SCHEMBL8601008 0.70
Allylthiourea SCHEMBL10882505 0.70
Allylthiourea SCHEMBL28555320 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 373 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2005520639-A 2005-07-14 JP claimed
EP-1485142-A1 CATHETER BALLOON FORMED OF EPTFE AND A DIENE POLYMER Advanced Cardiovascular Systems, Inc. (US) 2004-12-15 EP claimed
WO-2003080145-A1 CATHETER BALLOON FORMED OF ePTFE AND A DIENE POLYMER ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2003-10-02 WO claimed
US-20030180488-A1 Catheter balloon formed of ePTFE and a diene polymer ADVANCED CARDIOVASCULAR SYSTEMS, INC. 2003-09-25 US claimed
US-4146689-A SULFUR AND SULFUR-DONOR SANYO TRADING CO., LTD. (JP) 1979-03-27 US claimed
WO-2024015956-A1 RUBBER COMPOSITIONS CONTAINING PHLOROGLUCINOLIC RESINS FOR USE IN TIRE TREADS OF HEAVY VEHICLES SUMITOMO CHEMICAL ADVANCED TECHNOLOGIES, LLC, D.B.A. SUMIKA ELECTRONIC MATERIALS (US) 2024-01-18 WO disclosed
CN-117186509-A Rubber composition, rubber material, use thereof, and additive 大塚化学株式会社 2023-12-08 CN disclosed
CN-117186510-A Rubber composition, rubber material, use thereof, and additive 大塚化学株式会社 2023-12-08 CN disclosed
CN-112533991-B Rubber composition, rubber material, use thereof, and additive 大塚化学株式会社 2023-10-17 CN disclosed
CN-113227228-B Silane composition for forming polymer network 迈图高新材料公司 2023-09-05 CN disclosed
EP-3973001-A1 THIOESTER-FUNCTIONAL ORGANIC POLYMERS, METHOD FOR PREPARING AND COMPOSITIONS THEREOF Momentive Performance Materials Inc. (US) 2022-03-30 EP disclosed
US-11267955-B2 Polymer network forming silane compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2022-03-08 US disclosed
US-5159980-A WELL COMPLETION AND REMEDIAL METHODS UTILIZING RUBBER LATEX COMPOSITIONS HALLIBURTON COMPANY (US) 1992-11-03 US disclosed
WO-1992007028-A1 A TETRABENZYLTHIURAM DISULFIDE/UREA CURED ELASTOMERIC COMPOSITION UNIROYAL CHEMICAL COMPANY, INC. (US) 1992-04-30 WO disclosed
US-4273897-A Vulcanizable rubber compositions with amino acids SANYO TRADING CO., LTD. (JP) 1981-06-16 US disclosed
US-4202952-A Method of vulcanizing bromobutyl rubber with amino acids SANYO TRADING CO., LTD. (JP) 1980-05-13 US disclosed
US-4177337-A AMINO ACIDS AND PEROXY COMPOUNDS SANYO TRADING CO., LTD. (JP) 1979-12-04 US disclosed
US-4146689-A SULFUR AND SULFUR-DONOR SANYO TRADING CO., LTD. (JP) 1979-03-27 US disclosed
US-4020039-A CONJUGATED DIENE COPOLYMER, N,N'-M-PHENYLENEBIS(MALEIMIDE) POLYSAR LIMITED (CA) 1977-04-26 US disclosed
US-3852354-A HIGHER ALKYL THIUROM SULFIDE SUMITOMO CHEMICAL CO 1974-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11267955-B2 Polymer network forming silane compositions TSN, RIF1, TRHDE ALDH1A1 2479/4885TSHR 2329/4885KDM4A 2462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.