Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3608687 | 0.89 | MAPK8 (0.42) | MAPK8MAPK10KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3608683 | 0.82 | MAPK8 (0.42) | MAPK8MAPK10KDM4EALDH1A1MAPT | |
| SCHEMBL3600810 | 0.78 | PTPN1 (0.46) | KDM4EMAPK14MEN1KMT2AMAPT | |
| SCHEMBL3613736 | 0.78 | MAPK14 (0.46) | KDM4EALDH1A1MAPK14MEN1KMT2A | |
| SCHEMBL3609477 | 0.78 | MAPK14 (0.58) | KDM4EALDH1A1MAPK14LMNATRPM8 | |
| SCHEMBL3605131 | 0.78 | OPRD1 (0.54) | MAPK8MAPK10KDM4EALDH1A1MAPK14 | |
| SCHEMBL3601669 | 0.75 | MAPK1 (0.50) | KDM4EALDH1A1MAPTLMNATRPM8 | |
| SCHEMBL3605195 | 0.74 | TRPM8 (0.55) | KDM4EALDH1A1MAPK14LMNATRPM8 | |
| SCHEMBL3606735 | 0.74 | TRPM8 (0.41) | MAPK8MAPK10KDM4EALDH1A1TRPM8 | |
| SCHEMBL3612431 | 0.73 | SMN1; SMN2 (0.41) | KDM4EALDH1A1MAPK14GPR35DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835476-B2 | Synthesis of novel antimicrobials | WU FAN (CA) | 2014-09-16 | — | — | US | disclosed |
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | WU FAN | 2010-03-25 | — | — | US | disclosed |
| WO-2006092059-A1 | DESIGN AND SYNTHESIS OF NOVEL ANTIMICROBIALS | WU FAN (CA) | 2006-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | MLX, LPXN, TPX2 | MAPK8 3009/4885MAPK10 3344/4885KDM4E 4236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.