Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.63 |
| ▸ | BCR | P11274 | 3/20 | 0.63 |
| ▸ | PRKCA | P17252 | 2/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SRC | P12931 | 2/20 | 0.57 |
| ▸ | IKBKB | O14920 | 1/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.52 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 2/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.52 |
| ▸ | CAMK2D | Q13557 | 3/20 | 0.51 |
| ▸ | AURKA | O14965 | 4/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.50 |
| ▸ | KDR | P35968 | 2/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3616129 | 0.91 | ABL1 (0.56) | ABL1BCRPRKCASRCMAPK8 | |
| SCHEMBL3611706 | 0.87 | ABL1 (0.52) | ABL1BCRPRKCASRCMAPK8 | |
| SCHEMBL3613419 | 0.87 | ABL1 (0.57) | ABL1BCRPRKCANPC1RAB9A | |
| SCHEMBL3609221 | 0.87 | ABL1 (0.57) | ABL1BCRPRKCANPC1RAB9A | |
| SCHEMBL3598695 | 0.85 | JAK2 (0.56) | ABL1BCRPRKCASRCMAPK8 | |
| SCHEMBL5999668 | 0.84 | ABL1 (0.67) | ABL1BCRPRKCANPC1RAB9A | |
| SCHEMBL3609139 | 0.84 | PIK3CG (0.55) | ABL1BCRPRKCASRCMAPK8 | |
| SCHEMBL3607206 | 0.83 | CDC7 (0.59) | ABL1BCRSRCIKBKBGSK3B | |
| SCHEMBL3596098 | 0.81 | CDK9 (0.76) | ABL1MAPK8GSK3BPIK3CGCDK9 | |
| SCHEMBL25339113 | 0.80 | ABL1 (0.65) | ABL1BCRPRKCANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048597-A1 | Organic Compounds and Their Uses | NOVARTIS AG | 2010-02-25 | — | — | US | disclosed |
| US-20100048597-A1 | Organic Compounds and Their Uses | NOVARTIS AG | 2010-02-25 | — | — | US | disclosed |
| US-20100048597-A1 | Organic Compounds and Their Uses | NOVARTIS AG | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048597-A1 | Organic Compounds and Their Uses | OAT, OTC, AOX1 | ABL1 3215/4885BCR 3115/4885PRKCA 4612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.