Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 8/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.79 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30338888 | 1.00 | CYP2A6 (1.00) | CYP2A6CYP3A4ALDH1A1CYP1A2ATM | |
| Pyrimidine SCHEMBL28261125 | 0.92 | CYP2A6 (0.85) | CYP2A6CYP3A4ALDH1A1CYP1A2ATM | |
| SCHEMBL28013979 | 0.91 | CYP2A6 (0.83) | CYP2A6CYP3A4ALDH1A1CYP1A2ATM | |
| SCHEMBL6772005 | 0.89 | CYP2A6 (0.88) | CYP2A6CYP3A4ALDH1A1CYP1A2KDM4E | |
| SCHEMBL24492894 | 0.89 | CYP2A6 (0.79) | CYP2A6CYP3A4ALDH1A1CYP1A2ATM | |
| SCHEMBL24493051 | 0.89 | CYP2A6 (0.79) | CYP2A6CYP3A4ALDH1A1CYP1A2ATM | |
| SCHEMBL22428570 | 0.89 | CYP2A6 (0.79) | CYP2A6CYP3A4ALDH1A1CYP1A2ATM | |
| SCHEMBL24554680 | 0.89 | CYP2A6 (0.79) | CYP2A6CYP3A4ALDH1A1CYP1A2ATM | |
| SCHEMBL22428548 | 0.89 | CYP2A6 (0.79) | CYP2A6CYP3A4ALDH1A1CYP1A2ATM | |
| SCHEMBL22428534 | 0.89 | CYP2A6 (0.79) | CYP2A6CYP3A4ALDH1A1CYP1A2ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081670-A1 | N-PYRAZINYL-PHENYLSULPHONAMIDES AND THEIR USE IN THE TREATMENT OF CHEMOKINE MEDIATED DISEASES | BAXTER ANDREW | 2010-04-01 | — | — | US | claimed |
| US-10930853-B2 | Organic light-emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-02-23 | — | — | US | disclosed |
| US-10573827-B2 | Organic metal complex, and polymer, mixture, composition and organic electronic device containing same and use thereof | GUANGZHOU CHINARAY OPTOELECTRONICS MATERIALS LTD. (CN) | 2020-02-25 | — | — | US | disclosed |
| US-10364316-B2 | Conjugated polymer containing ethynyl crosslinking group, mixture, formulation, organic electronic device containing the same and application therof | GUANGZHOU CHINARAY OPTOELECTRONICS MATERIALS LTD. (CN) | 2019-07-30 | — | — | US | disclosed |
| EP-3466932-A1 | PRODUCTION METHOD FOR BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Kobelco Eco-Solutions Co., Ltd (JP) | 2019-04-10 | — | — | EP | disclosed |
| US-20180022865-A1 | CONJUGATED POLYMER CONTAINING ETHYNYL CROSSLINKING GROUP, MIXTURE COMPOSITION, ORGANIC ELECTRONIC DEVICE CONTINAING THE SAME AND APPLICATION THEROF | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2018-01-25 | — | — | US | disclosed |
| US-20170365789-A1 | COMPOUND, MIXTURE COMPRISING THE SAME, COMPOSITION AND ORGANIC ELECTRONIC DEVICE | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2017-12-21 | — | — | US | disclosed |
| US-9728805-B2 | Nonaqueous electrolyte and lithium secondary battery using the same | LG CHEM, LTD. (KR) | 2017-08-08 | — | — | US | disclosed |
| US-9728805-B2 | Nonaqueous electrolyte and lithium secondary battery using the same | LG CHEM, LTD. (KR) | 2017-08-08 | — | — | US | disclosed |
| US-20170155048-A1 | ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-06-01 | — | — | US | disclosed |
| EP-2541663-A1 | Nonaqueous electrolyte and lithium secondary battery using the same | LG Chem, Ltd. (KR) | 2013-01-02 | — | — | EP | disclosed |
| US-20100298345-A1 | SYNTHETIC COMPOUNDS AND DERIVATIVES AS MODULATORS OF SMOKING OR NICOTINE INGESTION AND LUNG CANCER | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2010-11-25 | — | — | US | disclosed |
| US-20100298345-A1 | SYNTHETIC COMPOUNDS AND DERIVATIVES AS MODULATORS OF SMOKING OR NICOTINE INGESTION AND LUNG CANCER | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2010-11-25 | — | — | US | disclosed |
| US-20100298345-A1 | SYNTHETIC COMPOUNDS AND DERIVATIVES AS MODULATORS OF SMOKING OR NICOTINE INGESTION AND LUNG CANCER | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2010-11-25 | — | — | US | disclosed |
| US-20100081670-A1 | N-PYRAZINYL-PHENYLSULPHONAMIDES AND THEIR USE IN THE TREATMENT OF CHEMOKINE MEDIATED DISEASES | BAXTER ANDREW | 2010-04-01 | — | — | US | disclosed |
| US-20080188527-A1 | Synthetic Compounds and Derivatives as Modulators of Smoking or Nicotine Ingestion and Lung Cancer | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2008-08-07 | — | — | US | disclosed |
| US-20080188527-A1 | Synthetic Compounds and Derivatives as Modulators of Smoking or Nicotine Ingestion and Lung Cancer | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2008-08-07 | — | — | US | disclosed |
| US-20080188527-A1 | Synthetic Compounds and Derivatives as Modulators of Smoking or Nicotine Ingestion and Lung Cancer | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2008-08-07 | — | — | US | disclosed |
| WO-2005092899-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2005-10-06 | — | — | WO | disclosed |
| WO-2005066162-A1 | SYNTHETIC COMPOUNDS AND DERIVATIVES AS MODULATORS OF SMOKING OR NICOTINE INGESTION AND LUNG CANCER | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2005-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188527-A1 | Synthetic Compounds and Derivatives as Modulators of Smoking or Nicotine Ingestion and Lung Cancer | CYP2A13, CYP2A6, CYP2B6 | CYP2A6 2/4885CYP3A4 45/4885ALDH1A1 762/4885 |
| US-20100081670-A1 | N-PYRAZINYL-PHENYLSULPHONAMIDES AND THEIR USE IN THE TREATMENT OF CHEMOKINE MEDIATED DISEASES | CCL11, CCL2, CCR2 | CYP2A6 1171/4885CYP3A4 1830/4885ALDH1A1 1544/4885 |
| US-10573827-B2 | Organic metal complex, and polymer, mixture, composition and organic electronic device containing same and use thereof | OCIAD1, OCIAD2, SEM1 | CYP2A6 652/4885CYP3A4 665/4885ALDH1A1 823/4885 |
| US-20100298345-A1 | SYNTHETIC COMPOUNDS AND DERIVATIVES AS MODULATORS OF SMOKING OR NICOTINE INGESTION AND LUNG CANCER | CYP2A13, CYP2A6, CYP2B6 | CYP2A6 2/4885CYP3A4 45/4885ALDH1A1 762/4885 |
| US-20170365789-A1 | COMPOUND, MIXTURE COMPRISING THE SAME, COMPOSITION AND ORGANIC ELECTRONIC DEVICE | DDT, DRD3, ICMT | CYP2A6 1104/4885CYP3A4 198/4885ALDH1A1 2400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.