Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.53 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3614418 | 0.94 | HSD11B1 (0.63) | HSD11B1ALDH1A1CYP2C9CYP2C19HSD17B1 | |
| SCHEMBL3611790 | 0.92 | HSD11B1 (0.61) | HSD11B1ALDH1A1CYP2C9CYP2C19HSD17B1 | |
| SCHEMBL3613133 | 0.91 | HSD11B1 (0.60) | HSD11B1ALDH1A1CYP2C9CYP2C19HSD17B1 | |
| SCHEMBL3606758 | 0.90 | HSD11B1 (0.65) | HSD11B1ALDH1A1CYP2C9CYP2C19HSD17B1 | |
| SCHEMBL3619100 | 0.90 | HSD11B1 (0.65) | HSD11B1ALDH1A1CYP2C9CYP2C19HSD17B1 | |
| SCHEMBL3618766 | 0.89 | HSD11B1 (0.57) | HSD11B1ALDH1A1CYP2C9CYP2C19HSD17B1 | |
| SCHEMBL3615845 | 0.88 | HSD11B1 (0.61) | HSD11B1ALDH1A1CYP2C9CYP2C19HSD17B1 | |
| SCHEMBL3625006 | 0.88 | HSD11B1 (0.63) | HSD11B1ALDH1A1CYP2C9CYP2C19HSD17B1 | |
| SCHEMBL3252937 | 0.88 | HSD11B1 (0.63) | HSD11B1ALDH1A1CYP2C9CYP2C19HSD17B1 | |
| SCHEMBL3619549 | 0.87 | HSD11B1 (0.70) | HSD11B1HSD17B1HSD17B2POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113435-A1 | INHIBITORS OF 11-BETA-HYDROXY STERIOD DEHYDROGENASE TYPE 1 | BIOVITRUM AB | 2010-05-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113435-A1 | INHIBITORS OF 11-BETA-HYDROXY STERIOD DEHYDROGENASE TYPE 1 | HSD11B1, HSD17B1, HSD3B1 | HSD11B1 1/4885ALDH1A1 59/4885CYP2C9 194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.