Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28450537 | 0.91 | HPGD (0.54) | KMT2AMEN1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL27800497 | 0.89 | LMNA (0.46) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL3754834 | 0.88 | KMT2A (0.56) | GSK3BKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL28413239 | 0.87 | ALDH1A1 (0.55) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL28405016 | 0.85 | ALDH1A1 (0.50) | GSK3BKMT2AKDM4EALDH1A1 | |
| SCHEMBL28635123 | 0.82 | CA1 (0.59) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL27821269 | 0.74 | PBRM1 (0.50) | KMT2ANPC1RAB9AMEN1MAPT | |
| SCHEMBL28421559 | 0.72 | KMT2A (0.36) | KMT2ARAB9AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL9449297 | 0.72 | HPGD (0.43) | GSK3BHSD17B3KMT2ANPC1RAB9A | |
| SCHEMBL8051337 | 0.69 | SMN1; SMN2 (0.70) | GSK3BHSD17B3KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7659353-B2 | Hyperbranched polymers | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2010-02-09 | — | — | US | disclosed |
| US-20050164899-A1 | Hyperbranched polymers | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2005-07-28 | — | — | US | disclosed |
| US-20030225232-A1 | Hyperbranched polymers | HONG KONG UNIVERSITY OF SCIENCE & TECHNOLOGY, THE (HK) | 2003-12-04 | — | — | US | disclosed |