Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 5/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30694356 | 0.81 | KDM4E (0.50) | HPGDGSK3BL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL27945048 | 0.78 | SMN1; SMN2 (0.63) | HPGDGSK3BL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL30080293 | 0.77 | ALDH1A1 (0.52) | HPGDACHEALDH1A1NR1H2NR1H3 | |
| SCHEMBL20010800 | 0.77 | CES2 (0.52) | HPGDACHENR1H2NR1H3RAB9A | |
| SCHEMBL2322402 | 0.75 | KMT2A (0.56) | HPGDL3MBTL1ALDH1A1POLBGAA | |
| SCHEMBL3892731 | 0.75 | GSK3B (0.64) | HPGDGSK3BL3MBTL1ALDH1A1GAA | |
| SCHEMBL105892 | 0.75 | HPGD (0.74) | HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL11910715 | 0.75 | HPGD (0.50) | HPGDACHEL3MBTL1ALDH1A1GAA | |
| SCHEMBL8018862 | 0.75 | HPGD (0.48) | HPGDACHEL3MBTL1ALDH1A1GAA | |
| SCHEMBL9716978 | 0.73 | HPGD (0.46) | HPGDACHEALDH1A1NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544812-A1 | BISPHOSPHONIC ACID DERIVATIVES AS ANTI-ARTHRITIC AGENTS. | UPJOHN CO (US) | 1993-06-09 | — | — | EP | disclosed |