Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.32 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10063493 | 0.84 | BACE1 (0.45) | KDM4ETSHRHSD17B10ALDH1A1LMNA | |
| SCHEMBL360907 | 0.78 | KDM4E (0.46) | KDM4ETSHRHSD17B10ALDH1A1LMNA | |
| SCHEMBL10062755 | 0.77 | KDM4E (0.37) | KDM4ETSHRHSD17B10ALDH1A1LMNA | |
| SCHEMBL10063495 | 0.74 | BACE1 (0.39) | KDM4ETSHRHSD17B10ALDH1A1LMNA | |
| SCHEMBL12006865 | 0.71 | GPR3 (0.38) | KDM4ETSHRHSD17B10ALDH1A1LMNA | |
| SCHEMBL10063600 | 0.71 | KDM4E (0.34) | KDM4ETSHRHSD17B10ALDH1A1LMNA | |
| SCHEMBL12145717 | 0.70 | KDM4E (0.41) | KDM4ETSHRHSD17B10ALDH1A1LMNA | |
| SCHEMBL10062640 | 0.70 | MEN1 (0.43) | KDM4ETSHRHSD17B10ALDH1A1LMNA | |
| SCHEMBL10063599 | 0.70 | KDM4E (0.39) | KDM4ETSHRHSD17B10ALDH1A1LMNA | |
| SCHEMBL12145720 | 0.68 | KDM4E (0.46) | KDM4ETSHRHSD17B10ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3476856-B1 | METHOD FOR PRODUCING HALOGEN-CROSSLINKED IRIDIUM DIMER | AIST (JP) | 2023-09-27 | — | — | EP | disclosed |
| US-10844086-B2 | Method for producing halogen-crosslinked iridium dimer | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2020-11-24 | — | — | US | disclosed |
| US-20190211041-A1 | METHOD FOR PRODUCING HALOGEN-CROSSLINKED IRIDIUM DIMER | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2019-07-11 | — | — | US | disclosed |
| US-9331290-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2016-05-03 | — | — | US | disclosed |
| US-9331290-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2016-05-03 | — | — | US | disclosed |
| US-9331290-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2016-05-03 | — | — | US | disclosed |
| US-20130112920-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| US-20130112920-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| US-20130112920-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-05-09 | — | — | US | disclosed |
| WO-2012007086-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007086-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2012-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190211041-A1 | METHOD FOR PRODUCING HALOGEN-CROSSLINKED IRIDIUM DIMER | MACF1, PPIP5K2, F2 | KDM4E 3741/4885TSHR 1577/4885HSD17B10 3480/4885 |
| US-10844086-B2 | Method for producing halogen-crosslinked iridium dimer | CYBA, CYBB, PPIB | KDM4E 3371/4885TSHR 2090/4885HSD17B10 3741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.