Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13061587 | 0.84 | ALOX5 (0.43) | TSHRALOX5PTPN1KDM4EALDH1A1 | |
| SCHEMBL361912 | 0.83 | LCK (0.45) | TSHRALOX5PTPN1KDM4EALDH1A1 | |
| SCHEMBL5158009 | 0.75 | ALDH1A1 (0.31) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL1334076 | 0.74 | MAPT (0.48) | TSHRMEN1TP53GAAMAPT | |
| SCHEMBL5647064 | 0.74 | GAA (0.42) | TSHRKDM4EALDH1A1MEN1GAA | |
| SCHEMBL26290022 | 0.73 | KDM4E (0.45) | TSHRPTPN1KDM4EALDH1A1HPGD | |
| SCHEMBL7128812 | 0.72 | MAPT (0.40) | KDM4EALDH1A1MEN1GAAMAPT | |
| SCHEMBL5107478 | 0.72 | NR4A2 (0.37) | TSHRKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL4798246 | 0.71 | PLA2G2A (0.41) | TSHRALOX5KDM4EALDH1A1HPGD | |
| SCHEMBL3238390 | 0.71 | PLA2G2A (0.39) | TSHRKDM4EPDK2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8500807-B2 | Photochromic intraocular lens | CARL ZEISS MEDITEC SAS (FR) | 2013-08-06 | — | — | US | disclosed |
| US-8500807-B2 | Photochromic intraocular lens | CARL ZEISS MEDITEC SAS (FR) | 2013-08-06 | — | — | US | disclosed |
| EP-1753838-B1 | POLYMERISABLE NAPHTHOPYRAN DERIVATIVES AND POLYMER MATERIALS OBTAINED FROM SAID DERIVATIVES | POLYMEREXPERT S A (FR) | 2012-03-14 | — | — | EP | disclosed |
| US-20100317805-A1 | POLYMERISABLE NAPHTHOPYRANE DERIVATIVES AND POLYMER MATERIALS OBTAINED FROM THESE DERIVATIVES | POLYMEREXPERT (FR) | 2010-12-16 | — | — | US | disclosed |
| EP-1834195-B9 | PHOTOCHROMIC INTRAOCULAR LENS | IOLTECHNOLOGIE PRODUCTION (FR) | 2010-07-21 | — | — | EP | disclosed |
| EP-1834195-B1 | PHOTOCHROMIC INTRAOCULAR LENS | IOLTECHNOLOGIE PRODUCTION (FR) | 2010-03-17 | — | — | EP | disclosed |
| US-20080200983-A1 | Photochromic Intraocular Lens | IOLTECHNOLOGIE-PRODUCTION (FR) | 2008-08-21 | — | — | US | disclosed |
| US-20080200983-A1 | Photochromic Intraocular Lens | IOLTECHNOLOGIE-PRODUCTION (FR) | 2008-08-21 | — | — | US | disclosed |
| US-20070197750-A1 | Polymerisable naphthopyrane derivatives and polymer materials obtained from these derivatives | POLYMEREXPERT (FR) | 2007-08-23 | — | — | US | disclosed |
| US-20070197750-A1 | Polymerisable naphthopyrane derivatives and polymer materials obtained from these derivatives | POLYMEREXPERT (FR) | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197750-A1 | Polymerisable naphthopyrane derivatives and polymer materials obtained from these derivatives | CCND3, H1-3, H1-0 | TSHR 4494/4885ALOX5 1758/4885PTPN1 3903/4885 |
| US-20100317805-A1 | POLYMERISABLE NAPHTHOPYRANE DERIVATIVES AND POLYMER MATERIALS OBTAINED FROM THESE DERIVATIVES | C1S, H1-0, H1-3 | TSHR 4627/4885ALOX5 1614/4885PTPN1 3751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.