Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | PLK1 | P53350 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 1/20 | 0.52 |
| ▸ | RXRB | P28702 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7637334 | 0.92 | ALDH1A1 (0.55) | ALDH1A1PLK1TDP1LMNAF2 | |
| SCHEMBL7631078 | 0.90 | ALDH1A1 (0.53) | ALDH1A1PLK1TDP1LMNAF2 | |
| SCHEMBL7635273 | 0.88 | ALDH1A1 (0.52) | ALDH1A1PLK1TDP1LMNAF2 | |
| SCHEMBL9073773 | 0.87 | ALDH1A1 (0.55) | ALDH1A1PLK1TDP1LMNARXRA | |
| SCHEMBL7633342 | 0.87 | ALDH1A1 (0.55) | ALDH1A1PLK1TDP1LMNARXRA | |
| SCHEMBL7628183 | 0.87 | ALDH1A1 (0.50) | ALDH1A1PLK1TDP1LMNAF2 | |
| SCHEMBL775750 | 0.86 | ALDH1A1 (0.64) | ALDH1A1PLK1TDP1LMNARXRA | |
| SCHEMBL7628937 | 0.85 | ALDH1A1 (0.48) | ALDH1A1PLK1TDP1LMNAF2 | |
| SCHEMBL7629576 | 0.84 | ALDH1A1 (0.52) | ALDH1A1PLK1TDP1LMNARXRA | |
| SCHEMBL131711 | 0.84 | LOXL2 (0.70) | ALDH1A1PLK1TDP1SMN1; SMN2LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426497-B2 | Synthesis of improved binders and modified tacticity | EVONIK ROEHM GMBH (DE) | 2013-04-23 | — | — | US | claimed |
| US-20140194585-A1 | BULK POLYMERIZATION OF (METH)ACRYLATE COPOLYMERS SOLUBLE UNDER AQUEOUS-ALKALINE CONDITIONS | EVONIK ROEHM GMBH (DE) | 2014-07-10 | — | — | US | disclosed |
| US-8426497-B2 | Synthesis of improved binders and modified tacticity | EVONIK ROEHM GMBH (DE) | 2013-04-23 | — | — | US | disclosed |
| US-20120157613-A1 | BULK POLYMERIZATION OF (METH)ACRYLATE COPOLYMERS SOLUBLE UNDER AQUEOUS-ALKALINE CONDITIONS | EVONIK ROEHM GMBH (DE) | 2012-06-21 | — | — | US | disclosed |
| US-20110269898-A1 | METHOD FOR SYNTHESIZING IMPROVED BINDERS HAVING A DEFINED GRAIN SIZE DISTRIBUTION | EVONIK ROEHM GMBH (DE) | 2011-11-03 | — | — | US | disclosed |
| US-20100298466-A1 | SYNTHESIS OF IMPROVED BINDERS AND MODIFIED TACTICITY | EVONIK ROEHM GMBH (DE) | 2010-11-25 | — | — | US | disclosed |
| US-6264865-B1 | Silicone rubber base compound for electrical wire coating, silicone composition for electrical wire coating, and process for the production of silicone rubber coated electrical wire | DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) | 2001-07-24 | — | — | US | disclosed |