Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL36204 | 0.88 | ALDH1A1 (0.64) | ALDH1A1PLK1TDP1RXRARXRB | |
| SCHEMBL7634659 | 0.88 | PLK1 (0.49) | ALDH1A1PLK1RAB9APOLBKMT2A | |
| SCHEMBL7628268 | 0.85 | TDP1 (0.52) | ALDH1A1TDP1RAB9ALMNAF2 | |
| SCHEMBL7623926 | 0.85 | RARB (0.51) | ALDH1A1PLK1POLBHPGDKMT2A | |
| SCHEMBL7637334 | 0.85 | ALDH1A1 (0.55) | ALDH1A1PLK1TDP1RXRARXRB | |
| SCHEMBL7634780 | 0.84 | ALDH1A1 (0.47) | ALDH1A1PLK1TDP1RXRARXRB | |
| SCHEMBL7637077 | 0.84 | THRA (0.54) | ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL7633998 | 0.83 | LMNA (0.65) | ALDH1A1TDP1RAB9ALMNAF2 | |
| SCHEMBL7627402 | 0.82 | THRA (0.56) | ALDH1A1TDP1KMT2AMEN1MAPT | |
| SCHEMBL7625811 | 0.82 | CA1 (0.56) | ALDH1A1RAB9ASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233014-A1 | ASYMMETRIC ORGANIC PEROXIDE, CROSSLINKING AGENT COMPRISING THE SAME, AND METHOD OF CROSSLINKING WITH THE SAME | NOF CORPORATION (JP) | 2002-08-21 | — | — | EP | disclosed |