Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 5/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.65 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16355872 | 0.92 | IGF1R (0.58) | IGF1RALOX15ADRB2ADORA3CHRM1 | |
| SCHEMBL3267119 | 0.90 | ALOX15 (0.58) | IGF1RALOX15ADRB2DRD1SLC6A2 | |
| SCHEMBL3234319 | 0.87 | IGF1R (0.63) | IGF1RALOX15ADORA3CHRM1ADRA2B | |
| SCHEMBL27677104 | 0.87 | IGF1R (0.50) | IGF1RALOX15PTGS2SLC28A3 | |
| SCHEMBL3624585 | 0.85 | IGF1R (0.65) | IGF1RALOX15HTR2AADRB2ADORA3 | |
| SCHEMBL26334743 | 0.84 | ALOX15 (0.61) | IGF1RALOX15ADRB2DRD1SLC6A2 | |
| SCHEMBL15583718 | 0.84 | ALOX15 (0.61) | IGF1RALOX15ADRB2DRD1SLC6A2 | |
| SCHEMBL25797957 | 0.84 | ALOX15 (0.61) | IGF1RALOX15ADRB2DRD1SLC6A2 | |
| SCHEMBL25184069 | 0.83 | OPRM1 (0.64) | IGF1RALOX15CHRM1DRD1SLC6A2 | |
| SCHEMBL7283191 | 0.82 | ADRB2 (0.76) | IGF1RALOX15ADRB2ADORA3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010134580-A1 | METHOD FOR PRODUCING AROMATIC FLUORINE COMPOUND AND NOVEL COMPOUND | 静岡県公立大学法人 (JP) | 2010-11-25 | — | — | WO | disclosed |