Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27221203 | 1.00 | KMT2A (0.39) | KMT2AMEN1RAB9ANPSR1CYP2C19 | |
| SCHEMBL2460578 | 1.00 | KMT2A (0.39) | KMT2AMEN1RAB9ANPSR1CYP2C19 | |
| SCHEMBL29469511 | 0.85 | MEN1 (0.38) | KMT2AMEN1RAB9ANPSR1MAPT | |
| SCHEMBL3594428 | 0.81 | CYP2C19 (0.41) | KMT2AMEN1RAB9ANPSR1CYP2C19 | |
| SCHEMBL4799382 | 0.80 | KMT2A (0.40) | KMT2AMEN1RAB9ANPSR1CYP2C19 | |
| SCHEMBL8475780 | 0.80 | CYP2C19 (0.41) | KMT2AMEN1RAB9ANPSR1CYP2C19 | |
| SCHEMBL7468842 | 0.80 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7468837 | 0.80 | ALDH1A1 (0.45) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL5559017 | 0.79 | MEN1 (0.39) | KMT2AMEN1RAB9ANPSR1CYP2C19 | |
| SCHEMBL18751773 | 0.76 | NPSR1 (0.37) | KMT2AMEN1RAB9ANPSR1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093811-A1 | HIV PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093811-A1 | HIV PROTEASE INHIBITORS | PRSS1, FURIN, SERPINB1 | KMT2A 1501/4885MEN1 2771/4885RAB9A 540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.