Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3621683 | 0.80 | KMT2A (0.39) | CYP2C19HIF1AKMT2AMEN1RAB9A | |
| SCHEMBL27221203 | 0.80 | KMT2A (0.39) | CYP2C19HIF1AKMT2AMEN1RAB9A | |
| SCHEMBL2460578 | 0.80 | KMT2A (0.39) | CYP2C19HIF1AKMT2AMEN1RAB9A | |
| SCHEMBL5559017 | 0.78 | MEN1 (0.39) | CYP2C19KMT2AMEN1RAB9ANPSR1 | |
| SCHEMBL8472299 | 0.75 | FABP5 (0.42) | KMT2A | |
| SCHEMBL18751773 | 0.75 | NPSR1 (0.37) | CYP2C19HIF1AKMT2AMEN1RAB9A | |
| SCHEMBL18751642 | 0.74 | MEN1 (0.36) | CYP2C19HIF1AKMT2AMEN1RAB9A | |
| SCHEMBL8736767 | 0.73 | MEN1 (0.43) | CYP2C19HIF1AKMT2AMEN1RAB9A | |
| SCHEMBL504005 | 0.73 | L3MBTL1 (0.55) | CYP2C19KMT2AMEN1RAB9ANPSR1 | |
| SCHEMBL1624311 | 0.72 | SMN1; SMN2 (0.51) | CYP2C19KMT2AMEN1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939554-A | Diarylaminopropanediol and diarylmethyl-oxazolidinone compounds | NDSU RESEARCH FOUNDATION (US) | 1999-08-17 | — | — | US | disclosed |
| US-5623087-A | Method for preparation of optically active diarylalanines | NDSU-RESEARCH FOUNDATION (US) | 1997-04-22 | — | — | US | disclosed |