Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | DGKA | P23743 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 4/20 | 0.49 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5349567 | 0.93 | EPHX2 (0.55) | CNR1EPHX2 | |
| Hydrochloric Acid SCHEMBL5349556 | 0.93 | EPHX2 (0.55) | CNR1EPHX2 | |
| SCHEMBL14445535 | 0.92 | DGKA (0.54) | L3MBTL1DGKAFAAHDNM1CASP2 | |
| Hydrochloric Acid SCHEMBL9298998 | 0.86 | CNR1 (0.43) | L3MBTL1DGKAFAAHCNR1CNR2 | |
| Hydrochloric Acid SCHEMBL11597133 | 0.86 | FAAH (0.60) | FAAHDNM1CASP2NAAAEPHX2 | |
| Hydrochloric Acid SCHEMBL11595724 | 0.86 | FAAH (0.60) | FAAHDNM1CASP2NAAAEPHX2 | |
| Hydrochloric Acid SCHEMBL11577427 | 0.86 | FAAH (0.60) | FAAHDNM1CASP2NAAAEPHX2 | |
| Hydrochloric Acid SCHEMBL11595919 | 0.86 | FAAH (0.60) | FAAHDNM1CASP2NAAAEPHX2 | |
| Hydrochloric Acid SCHEMBL11595739 | 0.86 | FAAH (0.60) | FAAHDNM1CASP2NAAAEPHX2 | |
| Hydrochloric Acid SCHEMBL3462945 | 0.86 | DGKA (0.65) | DGKADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1775373-B2 | Fiber-treating composition | KAO CORP (JP) | 2013-06-19 | — | — | EP | disclosed |
| US-7670388-B2 | Fiber-treating composition | KAO CORPORATION (JP) | 2010-03-02 | — | — | US | disclosed |
| EP-1775373-B1 | Fiber-treating composition | KAO CORP (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-20070089243-A1 | Fiber-treating composition | KAO CORPORATION (JP) | 2007-04-26 | — | — | US | disclosed |
| EP-1775373-A1 | Fiber-treating composition | Kao Corporation (JP) | 2007-04-18 | — | — | EP | disclosed |
| US-20050242320-A1 | Fiber treating composition | KAO CORPORATION (JP) | 2005-11-03 | — | — | US | disclosed |
| EP-1586694-A2 | Fiber treating composition | Kao Corporation (JP) | 2005-10-19 | — | — | EP | disclosed |
| US-5282983-A | Formed by neutralizing and/or quaternizing tertiary amine containing ester and amide groups and two long alkyl chains | KAO CORPORATION (JP) | 1994-02-01 | — | — | US | disclosed |