Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320236 | 0.74 | GAA (0.30) | GAAL3MBTL1 | |
| SCHEMBL3760207 | 0.62 | — | — | |
| SCHEMBL289296 | 0.61 | — | — | |
| SCHEMBL1817087 | 0.60 | MAPT (0.30) | — | |
| SCHEMBL4961797 | 0.60 | GAA (0.46) | GAAL3MBTL1 | |
| SCHEMBL4439298 | 0.59 | — | — | |
| SCHEMBL3771398 | 0.59 | GAA (0.40) | GAAL3MBTL1 | |
| SCHEMBL244419 | 0.59 | GAA (0.39) | GAAL3MBTL1 | |
| SCHEMBL7159276 | 0.59 | — | — | |
| SCHEMBL989793 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100310471-A1 | ANTIOXIDANT AND PARAMAGNETIC HEPARIN-NITROXIDE DERIVATIVES | Johannes Gutenberg-Universität Mainz (DE) | 2010-12-09 | — | — | US | claimed |
| EP-2217589-A2 | MODULATORS OF OCULAR OXIDATIVE STRESS | ReVision Therapeutics, Inc. (US) | 2010-08-18 | — | — | EP | claimed |
| US-20090253745-A1 | MODULATORS OF OCULAR OXIDATIVE STRESS | SIRION THERAPEUTICS, INC. (US) | 2009-10-08 | — | — | US | claimed |
| WO-2009070693-A2 | MODULATORS OF OCULAR OXIDATIVE STRESS | SIRION THERAPEUTICS, INC (US) | 2009-06-04 | — | — | WO | claimed |
| WO-2009027056-A2 | ANTIOXIDANT AND PARAMAGNETIC HEPARIN-NITROXIDE DERIVATIVES | JOHANNES GUTENBERG-UNIVERSITÄT MAINZ vertreten durch den Präsidenten (DE) | 2009-03-05 | — | — | WO | claimed |
| EP-2030624-A1 | Antioxidant and paramagnetic heparin-nitroxide derivatives | Johannes Gutenberg Universität (DE) | 2009-03-04 | — | — | EP | claimed |
| US-20100310471-A1 | ANTIOXIDANT AND PARAMAGNETIC HEPARIN-NITROXIDE DERIVATIVES | Johannes Gutenberg-Universität Mainz (DE) | 2010-12-09 | — | — | US | disclosed |
| EP-2217589-A2 | MODULATORS OF OCULAR OXIDATIVE STRESS | ReVision Therapeutics, Inc. (US) | 2010-08-18 | — | — | EP | disclosed |
| US-20090253745-A1 | MODULATORS OF OCULAR OXIDATIVE STRESS | SIRION THERAPEUTICS, INC. (US) | 2009-10-08 | — | — | US | disclosed |
| WO-2009070693-A2 | MODULATORS OF OCULAR OXIDATIVE STRESS | SIRION THERAPEUTICS, INC (US) | 2009-06-04 | — | — | WO | disclosed |
| WO-2009027056-A2 | ANTIOXIDANT AND PARAMAGNETIC HEPARIN-NITROXIDE DERIVATIVES | JOHANNES GUTENBERG-UNIVERSITÄT MAINZ vertreten durch den Präsidenten (DE) | 2009-03-05 | — | — | WO | disclosed |
| EP-2030624-A1 | Antioxidant and paramagnetic heparin-nitroxide derivatives | Johannes Gutenberg Universität (DE) | 2009-03-04 | — | — | EP | disclosed |
| US-4925652-A | NUCLEAR MAGNETIC RESONANCE | SCHERING AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| US-4845090-A | NUCLEAR MAGNETIC RESONANCE | SCHERING AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253745-A1 | MODULATORS OF OCULAR OXIDATIVE STRESS | GPX4, GPX1, ALDH1A2 | GAA 656/4885L3MBTL1 4703/4885 |
| US-20100310471-A1 | ANTIOXIDANT AND PARAMAGNETIC HEPARIN-NITROXIDE DERIVATIVES | PRDX3, PRDX5, PRDX1 | GAA 580/4885L3MBTL1 3110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.