SCHEMBL362287

SCHEMBL362287

N=C(N)On1nnc2cccnc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.37
MGLL Q99685 4/20 0.37
BRD4 O60885 2/20 0.37
TUBB4A P04350 1/20 0.35
TUBB P07437 1/20 0.35
TUBA3C P0DPH7 1/20 0.35
TUBA1B P68363 1/20 0.35
TUBA4A P68366 1/20 0.35
TUBB4B P68371 1/20 0.35
TUBB3 Q13509 1/20 0.35
TUBB2A Q13885 1/20 0.35
TUBB8 Q3ZCM7 1/20 0.35
TUBA3E Q6PEY2 1/20 0.35
TUBA1A Q71U36 1/20 0.35
TUBA1C Q9BQE3 1/20 0.35
TUBB6 Q9BUF5 1/20 0.35
TUBB2B Q9BVA1 1/20 0.35
TUBB1 Q9H4B7 1/20 0.35
PARP1 P09874 1/20 0.33
DGAT1 O75907 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7012103 0.81 FAAH (0.44) FAAHMGLLBRD4TUBB4ATUBB
SCHEMBL26599029 0.79 FAAH (0.43) FAAHMGLLBRD4TUBB4ATUBB
SCHEMBL24582801 0.78 FAAH (0.42) FAAHMGLLBRD4TUBB4ATUBB
SCHEMBL9996736 0.78 FAAH (0.45) FAAHMGLLTUBB4ATUBBTUBA3C
SCHEMBL12435588 0.78 FAAH (0.45) FAAHMGLLBRD4KRASRAB9A
Hydrochloric Acid SCHEMBL31023950 0.77 FAAH (0.41) FAAHMGLLBRD4TUBB4ATUBB
SCHEMBL2293707 0.76 FAAH (0.43) FAAHMGLLBRD4KRASSIRT2
SCHEMBL2295830 0.76 FAAH (0.43) FAAHMGLLBRD4TUBB4ATUBB
SCHEMBL2217546 0.76 FAAH (0.43) FAAHMGLLBRD4KRASSIRT2
SCHEMBL23974808 0.76 FAAH (0.49) FAAHMGLLTUBB4ATUBBTUBA3C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3612524-B1 6-PYRIMIDIN-ISOINDOLE DERIVATIVE AS ERK1/2 INHIBITOR OTSUKA PHARMA CO LTD (JP) 2024-08-28 EP claimed
EP-3538596-B1 ADHESIVE KIT OF SEVERAL PRESSURE SENSITIVE ADHESIVE LAYERS TESA SE (DE) 2021-01-20 EP claimed
US-20190284446-A1 ADHESIVE SYSTEM MADE OF A MULTIPLICITY OF PRESSURE-SENSITVE ADHESIVE LAYERS TESA SE (DE) 2019-09-19 US claimed
US-11359115-B2 Adhesive system made of a multiplicity of pressure-sensitive adhesive layers TESA SE (DE) 2022-06-14 US disclosed
US-20190284446-A1 ADHESIVE SYSTEM MADE OF A MULTIPLICITY OF PRESSURE-SENSITVE ADHESIVE LAYERS TESA SE (DE) 2019-09-19 US disclosed
WO-2012009226-A1 SUBSTITUTED IMIDAZOLONES, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF USE MERCK SHARP & DOHME CORP. (US) 2012-01-19 WO disclosed