Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CPT1A | P50416 | 3/20 | 0.43 |
| ▸ | CPT1B | Q92523 | 3/20 | 0.43 |
| ▸ | CPT2 | P23786 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3617279 | 0.93 | ALDH1A1 (0.47) | ALDH1A1PKMKMT2ATSHRCPT1A | |
| SCHEMBL3623663 | 0.92 | TSHR (0.51) | ALDH1A1PKMKMT2ATSHRCPT1A | |
| Trifluoroacetic Acid SCHEMBL3626187 | 0.87 | CPT1A (0.44) | ALDH1A1PKMKMT2ATSHRCPT1A | |
| SCHEMBL3626085 | 0.85 | ALDH1A1 (0.52) | ALDH1A1PKMKMT2ATSHRCPT1A | |
| SCHEMBL3620704 | 0.79 | ALDH1A1 (0.43) | ALDH1A1PKMKMT2ATSHRCPT1A | |
| SCHEMBL3626204 | 0.78 | KMT2A (0.49) | ALDH1A1PKMKMT2ATSHRCPT1A | |
| Trifluoroacetic Acid SCHEMBL3618819 | 0.78 | HTR6 (0.50) | ALDH1A1PKMTSHRCPT1ACPT1B | |
| SCHEMBL3623725 | 0.77 | KMT2A (0.55) | ALDH1A1PKMKMT2ATSHRPOLB | |
| SCHEMBL3625987 | 0.73 | KMT2A (0.52) | ALDH1A1PKMKMT2ATSHRCPT1A | |
| Trifluoroacetic Acid SCHEMBL3619410 | 0.73 | HTR6 (0.59) | ALDH1A1PKMCPT1ACPT1BCPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046741-B1 | INDOLES AS 5-HT6 MODULATORS | PROXIMAGEN LTD (GB) | 2012-10-31 | — | — | EP | disclosed |
| US-7812017-B2 | 4-substituted indole and indoline compounds | BIOVITRUM AB (PUBL.) (SE) | 2010-10-12 | — | — | US | disclosed |
| EP-2046741-A1 | INDOLES AS 5-HT6 MODULATORS | BIOVITRUM AB (publ) (SE) | 2009-04-15 | — | — | EP | disclosed |
| US-20080032968-A1 | New compounds | PROXIMAGEN NEUROSCIENCE PLC (GB) | 2008-02-07 | — | — | US | disclosed |
| WO-2008003703-A1 | INDOLES AS 5-HT6 MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080032968-A1 | New compounds | HTR6, HTR1B, HTR1A | ALDH1A1 917/4885PKM 1474/4885KMT2A 3558/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.