Biphenyl

Biphenyl

SCHEMBL3623007

C1CCC(C2CCCCC2)CC1.OBO

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
SLC18A3 Q16572 2/20 0.39
TSHR P16473 1/20 0.35
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
HSD11B1 P28845 1/20 0.35
HSD17B10 Q99714 1/20 0.32
EPHX1 P07099 5/20 0.30
CYP3A4 P08684 2/20 0.30
NPC1 O15118 2/20 0.30
RAB9A P51151 2/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
KDM4E B2RXH2 1/20 0.30
EPHX2 P34913 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL8851247 0.84 ALDH1A1 (0.73) ALDH1A1SLC18A3TSHRCES2CES1
SCHEMBL7739675 0.83 ALDH1A1 (0.89) ALDH1A1SLC18A3TSHRCES2CES1
SCHEMBL2999797 0.83 ALDH1A1 (0.89) ALDH1A1SLC18A3TSHRCES2CES1
SCHEMBL6683741 0.83 ALDH1A1 (0.89) ALDH1A1SLC18A3TSHRCES2CES1
SCHEMBL241806 0.83 ALDH1A1 (0.89) ALDH1A1SLC18A3TSHRCES2CES1
SCHEMBL2278796 0.83 ALDH1A1 (0.89) ALDH1A1SLC18A3TSHRCES2CES1
SCHEMBL7741464 0.83 ALDH1A1 (0.89) ALDH1A1SLC18A3TSHRCES2CES1
SCHEMBL22284066 0.83 ALDH1A1 (0.89) ALDH1A1SLC18A3TSHRCES2CES1
SCHEMBL22284064 0.83 ALDH1A1 (0.89) ALDH1A1SLC18A3TSHRCES2CES1
Biphenyl SCHEMBL2997707 0.83 ALDH1A1 (0.89) ALDH1A1SLC18A3TSHRCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2508343-B1 MULTILAYER STRUCTURE AND METHOD FOR PRODUCING SAME KURARAY CO (JP) 2020-03-11 EP disclosed
EP-3026050-B1 NOVEL TRIAZINE DERIVATIVE CARNA BIOSCIENCES INC (JP) 2018-11-07 EP disclosed
US-9656995-B2 Triazine derivative CARNA BIOSCIENCES, INC. (JP) 2017-05-23 US disclosed
US-20160221991-A1 NOVEL TRIAZINE DERIVATIVE CARNA BIOSCIENCES, INC. (JP) 2016-08-04 US disclosed
EP-3048102-A1 NOVEL TRIAZINE DERIVATIVE Carna Biosciences Inc. (JP) 2016-07-27 EP disclosed
US-20160207906-A1 NOVEL 2,6-DIAMINOPYRIMIDINE DERIVATIVE CARNA BIOSCIENCES, INC. (JP) 2016-07-21 US disclosed
EP-3042899-A1 NOVEL 2,6-DIAMINOPYRIMIDINE DERIVATIVE Carna Biosciences Inc. (JP) 2016-07-13 EP disclosed
US-20160168122-A1 NOVEL TRIAZINE DERIVATIVE CARNA BIOSCIENCES, INC. (JP) 2016-06-16 US disclosed
EP-3026050-A1 NOVEL TRIAZINE DERIVATIVE Carna Biosciences Inc. (JP) 2016-06-01 EP disclosed
US-9186873-B2 Multilayered structure and method for producing the same KURARAY CO., LTD. (JP) 2015-11-17 US disclosed
US-20120237747-A1 MULTILAYERED STRUCTURE AND METHOD FOR PRODUCING THE SAME KURARAY CO., LTD. (JP) 2012-09-20 US disclosed
US-20120204940-A1 POLYVINYL ACETAL LAMINATE AND USE THEREOF KURARAY CO., LTD. (JP) 2012-08-16 US disclosed
EP-2463095-A1 POLYVINYL ACETAL LAMINATE AND USE THEREOF Kuraray Co., Ltd. (JP) 2012-06-13 EP disclosed
EP-2174981-A1 Resin composition and multi-layer structures Kuraray Co., Ltd. (JP) 2010-04-14 EP disclosed
US-7534829-B2 Resin composition and multi-layer structures KURARAY CO., LTD. (JP) 2009-05-19 US disclosed
EP-1108653-B1 FUEL CONTAINER KURARAY CO (JP) 2007-05-16 EP disclosed
US-20050147778-A1 Resin composition and multi-layer structures KURARAY CO., LTD. (JP) 2005-07-07 US disclosed
EP-1479725-A1 RESIN COMPOSITION AND MULTI-LAYER STRUCTURES Kuraray Co., Ltd. (JP) 2004-11-24 EP disclosed
US-6398059-B1 Fuel container KURARAY CO., LTD. (JP) 2002-06-04 US disclosed
EP-1108653-A1 FUEL CONTAINER KURARAY CO., LTD. (JP) 2001-06-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160207906-A1 NOVEL 2,6-DIAMINOPYRIMIDINE DERIVATIVE DPYD, QDPR, PARP2 ALDH1A1 303/4885SLC18A3 4631/4885TSHR 2432/4885
US-20160221991-A1 NOVEL TRIAZINE DERIVATIVE BAZ2A, BAZ2B, DOT1L ALDH1A1 1069/4885SLC18A3 4308/4885TSHR 206/4885
US-20160168122-A1 NOVEL TRIAZINE DERIVATIVE CBR3, HDAC3, SSTR3 ALDH1A1 2700/4885SLC18A3 2746/4885TSHR 78/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.