SCHEMBL3623072

SCHEMBL3623072

CCOC(=O)C1(O)C=CC(c2ccccc2)=CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 5/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
OPRD1 P41143 3/20 0.39
OPRK1 P41145 3/20 0.39
SLC22A1 O15245 1/20 0.39
SLC6A4 P31645 1/20 0.39
ADRA1A P35348 1/20 0.39
KCNH2 Q12809 1/20 0.39
TSHR P16473 1/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
HTT P42858 1/20 0.37
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10442548 0.90 TSHR (0.35) OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1
SCHEMBL28872247 0.85 CACNA1F (0.39) OPRM1SMN1; SMN2OPRD1NPC1RAB9A
SCHEMBL10589794 0.85 MAPT (0.39) TSHRMEN1KMT2AHTTKDM4E
SCHEMBL9487768 0.85 MAPT (0.39) TSHRMEN1KMT2AHTTKDM4E
SCHEMBL9852431 0.85 TSHR (0.43) TSHRKDM4EALDH1A1LMNA
SCHEMBL1966610 0.85 OPRM1 (0.41) OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1
SCHEMBL28757628 0.85 TSHR (0.41) OPRM1SMN1; SMN2OPRD1OPRK1SLC22A1
SCHEMBL8970782 0.85 MEN1 (0.38) SMN1; SMN2OPRK1SLC6A4TSHRNPC1
SCHEMBL9489470 0.84 CHRM2 (0.31)
SCHEMBL27694521 0.83 CYP3A4 (0.39) SMN1; SMN2TSHRMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8304035-B2 Liquid crystal display MERCK PATENT GMBH (DE) 2012-11-06 US disclosed
US-20100309423-A1 Liquid Crystal Display MERCK PATENT GESELLSCHAFT (DE) 2010-12-09 US disclosed
EP-1636324-A1 POLYMERS FOR USE AS ALIGNMENT LAYERS IN LIQUID CRYSTAL DEVICES ECSIBEO PPF2 AB (SE) 2006-03-22 EP disclosed
WO-2004113470-A1 POLYMERS FOR USE AS ALIGNMENT LAYERS IN LIQUID CRYSTAL DEVICES ECSIBEO PPF2 AB (SE) 2004-12-29 WO disclosed
EP-0228703-B1 FERROELECTRIC LIQUID CRYSTAL POLYMER IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-03-10 EP disclosed
EP-0362714-A2 Liquid-crystalline compounds and liquid-crystalline polymers IDEMITSU KOSAN COMPANY LIMITED (JP) 1990-04-11 EP disclosed
US-4913839-A USABLE AT ROOM TEMPERATURE; FAST RESPONSE SPEED; DISPLAYING MOTION PICTURES; SUITABLE FOR LARGE OR CURVED SCREENS IDEMITSU KOSAN CO., LTD. (JP) 1990-04-03 US disclosed
US-4844835-A FAST RESPONSE, DISPLAYING MOTION PICTURES IDENITSU KOSAN CO., LTD. (JP) 1989-07-04 US disclosed
EP-0228703-A2 Ferroelectric liquid crystal polymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-07-15 EP disclosed