Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3623072 | 0.85 | OPRM1 (0.40) | MEN1KMT2AHTTCYP2C19CYP1A2 | |
| SCHEMBL19746580 | 0.84 | MEN1 (0.42) | MEN1KMT2AHTTCYP2C19CYP1A2 | |
| SCHEMBL5182782 | 0.84 | MEN1 (0.39) | MEN1KMT2AHTTCYP2C19CYP1A2 | |
| SCHEMBL1119645 | 0.83 | THRB (0.35) | — | |
| SCHEMBL29053322 | 0.82 | MEN1 (0.38) | MEN1KMT2AHTTCYP2C19CYP1A2 | |
| SCHEMBL27656088 | 0.81 | MEN1 (0.40) | MEN1KMT2AHTTCYP2C19CYP1A2 | |
| SCHEMBL5984481 | 0.81 | MEN1 (0.37) | MEN1KMT2AHTTCYP2C19CYP1A2 | |
| SCHEMBL27566410 | 0.81 | MEN1 (0.37) | MEN1KMT2AHTTCYP2C19CYP1A2 | |
| SCHEMBL10442548 | 0.80 | TSHR (0.35) | MEN1KMT2AHTTCYP2C19CYP1A2 | |
| SCHEMBL27760470 | 0.80 | GAA (0.40) | MEN1KMT2AHTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100360512-C | Biphenylmethyl-thiazolidinediones and analogues thereof and their use as PPAR-gamma activators | GALDERMA RES & DEV (FR) | 2008-01-09 | — | — | CN | disclosed |
| CN-1639138-A | Biphenylmethyl-thiazolidinediones and analogues and their use as PPAR-gamma activators | GALDERMA RES & DEV (FR) | 2005-07-13 | — | — | CN | disclosed |
| CN-1150589-A | New sulfuric acid esters of sugar alcohols | HOFFMANN LA ROCHE (CH) | 1997-05-28 | — | — | CN | disclosed |
| EP-0493601-B1 | LIQUID-CRYSTAL COPOLYMER, PRODUCTION THEREOF, DIENE COMPOUND USED IN SAID PRODUCTION, AND PRODUCTION OF SAID COMPOUND | IDEMITSU KOSAN CO (JP) | 1996-03-20 | — | — | EP | disclosed |
| US-5451339-A | Liquid crystal monomeric compound and liquid crystal polymer compound modified therewith | SHOWA SHELL SEKIYU KABUSHIKI KAISHA (JP) | 1995-09-19 | — | — | US | disclosed |
| US-5425897-A | Electrooptics | IDEMITSU KOSAN CO., LTD. (JP) | 1995-06-20 | — | — | US | disclosed |
| US-5380915-A | Copolymers of polydimethylsiloxane with diene ethers | IDEMITSU KOSAN CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| US-5281685-A | Polyether pendant groups, polysiloxane repeating units | IDEMITSU KOSAN CO., LTD. (JP) | 1994-01-25 | — | — | US | disclosed |
| US-5230830-A | Ferroelectricity | THE SECRTEARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1993-07-27 | — | — | US | disclosed |
| EP-0391956-B1 | CYANOHYDRIN DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MATERIALS AND DEVICES | SECR DEFENCE BRIT (GB) | 1993-04-21 | — | — | EP | disclosed |
| US-5133896-A | Cyanohyorin derivatives and their use in liquid crystal materials and devices | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1992-07-28 | — | — | US | disclosed |
| EP-0493601-A1 | LIQUID-CRYSTAL COPOLYMER, PRODUCTION THEREOF, DIENE COMPOUND USED IN SAID PRODUCTION, AND PRODUCTION OF SAID COMPOUND | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-07-08 | — | — | EP | disclosed |
| EP-0391956-A1 | CYANOHYDRIN DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MATERIALS AND DEVICES. | SECR DEFENCE BRIT (GB) | 1990-10-17 | — | — | EP | disclosed |
| WO-1989005792-A1 | CYANOHYDRIN DERIVATIVES AND THEIR USE IN LIQUID CRYSTAL MATERIALS AND DEVICES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1989-06-29 | — | — | WO | disclosed |