Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 12/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 12/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 12/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 12/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969959 | 0.86 | FAAH (0.47) | TSHRLMNATP53POLB | |
| SCHEMBL3623072 | 0.85 | OPRM1 (0.40) | TSHRALDH1A1LMNAKDM4E | |
| SCHEMBL10903896 | 0.84 | CNR2 (0.42) | TSHRALDH1A1LMNACHRM2CHRM4 | |
| SCHEMBL4128084 | 0.84 | THRB (0.40) | TSHRALDH1A1TP53CYP3A4HSD17B10 | |
| SCHEMBL9680780 | 0.80 | TSHR (0.40) | TSHRALDH1A1LMNACHRM2CHRM4 | |
| SCHEMBL10589794 | 0.79 | MAPT (0.39) | TSHRALDH1A1LMNACHRM2CHRM4 | |
| SCHEMBL27999808 | 0.79 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPK1 | |
| SCHEMBL9487768 | 0.79 | MAPT (0.39) | TSHRALDH1A1LMNACHRM2CHRM4 | |
| SCHEMBL10442548 | 0.79 | TSHR (0.35) | TSHRALDH1A1LMNAKDM4E | |
| SCHEMBL8970782 | 0.79 | MEN1 (0.38) | TSHRALDH1A1CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0422996-A2 | Liquid crystal compound | Showa Shell Sekiyu Kabushiki Kaisha (JP) | 1991-04-17 | — | — | EP | disclosed |