SCHEMBL3623263

SCHEMBL3623263

Clc1cccnc1-c1c[c][nH]n1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 1/20 0.35
CNR2 P34972 1/20 0.33
METAP2 P50579 1/20 0.33
S100A4 P26447 1/20 0.33
CDC25B P30305 1/20 0.33
ADRA2A P08913 1/20 0.31
ADRA2C P18825 1/20 0.31
ADRA1D P25100 1/20 0.31
ADRA1A P35348 1/20 0.31
ADRA1B P35368 1/20 0.31
RPS6KA5 O75582 1/20 0.31
RORB Q92753 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3632419 0.79 METAP2 (0.54) CNR2METAP2ADRA1A
SCHEMBL3629372 0.79 METAP2 (0.33) METAP2
SCHEMBL3627348 0.79 GABRG2 (0.38) METAP2
SCHEMBL3632883 0.79 CDC25B (0.36) METAP2CDC25BADRA2AADRA2CADRA1D
SCHEMBL4637478 0.76 CBFB (0.37) METAP2
SCHEMBL4636926 0.73 IDO1 (0.52)
SCHEMBL2306238 0.72 DPP4 (0.48) DPP4CNR2METAP2S100A4CDC25B
SCHEMBL27967733 0.71 DPP4 (0.37) DPP4CNR2METAP2S100A4CDC25B
SCHEMBL3623272 0.70 IDO1 (0.53) CNR2ADRA1A
SCHEMBL4633189 0.70 DPP4 (0.47) DPP4CNR2METAP2S100A4CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104125773-A N-arylamidine substituted trifluoroethyl sulfide derivatives as acaricides and insecticides BAYER CROPSCIENCE AG 2014-10-29 CN claimed
CN-103987260-A Active ingredient combinations having insecticidal and acaricidal properties BAYER IP GMBH 2014-08-13 CN claimed
CN-103619173-A Active compound combinations comprising (thio) carboxamide derivatives and insecticidal, acaricidal or nematicidal active compounds BAYER IP GMBH 2014-03-05 CN claimed
CN-103597077-A Soybean event SYHT0H2 and compositions and methods for detection thereof SYNGENTA PARTICIPATIONS AG 2014-02-19 CN claimed
CN-105658638-A compounds with insecticidal activity 拜耳作物科学股份公司 2016-06-08 CN disclosed
CN-105530815-A Use of combinations comprising host defense inducers and biological control agents for controlling bacterial harmful organisms in useful plants BAYER CROPSCIENCE AG 2016-04-27 CN disclosed
CN-105451563-A Compositions comprising biological control agents BAYER CROPSCIENCE AG 2016-03-30 CN disclosed
CN-105451559-A Binary fungicidal and bactericidal combinations BAYER CROPSCIENCE AG 2016-03-30 CN disclosed
CN-105392365-A Heterocyclic compounds known and new as pest control agents BAYER CROPSCIENCE AG 2016-03-09 CN disclosed
CN-105324031-A Active substance combinations having insecticidal properties BAYER CROPSCIENCE AG 2016-02-10 CN disclosed
CN-105208865-A Use of dithiine-tetracarboximides for controlling bacterial harmful organisms in useful plants BAYER CROPSCIENCE AG 2015-12-30 CN disclosed
CN-105189483-A Alkoximino-substituted anthranilic acid diamides as pesticides BAYER CROPSCIENCE AG 2015-12-23 CN disclosed
CN-103987260-A Active ingredient combinations having insecticidal and acaricidal properties BAYER IP GMBH 2014-08-13 CN disclosed
CN-103649049-A Substituted 3-(biphenyl-3-yl)-8,8-difluoro-hydroxy-1-azaspiro[4.5]dec-3-en-2-ones for therapy and halogen-substituted spirocyclic ketoenols BAYER IP GMBH 2014-03-19 CN disclosed
CN-103619173-A Active compound combinations comprising (thio) carboxamide derivatives and insecticidal, acaricidal or nematicidal active compounds BAYER IP GMBH 2014-03-05 CN disclosed
CN-103597077-A Soybean event SYHT0H2 and compositions and methods for detection thereof SYNGENTA PARTICIPATIONS AG 2014-02-19 CN disclosed
EP-2144898-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2010-01-20 EP disclosed
WO-2008130021-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-30 WO disclosed
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 EP disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed