Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 7/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 7/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 7/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 7/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3623263 | 0.79 | DPP4 (0.35) | METAP2 | |
| SCHEMBL3629372 | 0.79 | METAP2 (0.33) | METAP2 | |
| SCHEMBL3632883 | 0.79 | CDC25B (0.36) | METAP2 | |
| SCHEMBL3632419 | 0.79 | METAP2 (0.54) | METAP2NPC1 | |
| SCHEMBL4637478 | 0.76 | CBFB (0.37) | METAP2CBFBNPC1 | |
| SCHEMBL15624391 | 0.72 | TDP1 (0.44) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL2147475 | 0.71 | GABRG2 (0.39) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL29901544 | 0.70 | KDM4E (0.54) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| SCHEMBL27582944 | 0.70 | KDM4E (0.54) | GABRG2GABRB3GABRA5GABRA3GABRA1 | |
| Hydrochloric Acid SCHEMBL31067832 | 0.68 | KDM4E (0.52) | GABRG2GABRB3GABRA5GABRA3GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144898-A2 | HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | Sumitomo Chemical Company, Limited (JP) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008130021-A2 | HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2008-10-30 | — | — | WO | disclosed |