Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9199145 | 0.82 | — | — | |
| SCHEMBL24215052 | 0.80 | — | — | |
| SCHEMBL24215054 | 0.80 | — | — | |
| SCHEMBL28333223 | 0.78 | — | — | |
| SCHEMBL28318945 | 0.76 | ALDH1A1 (0.49) | ALDH1A1 | |
| SCHEMBL6429233 | 0.75 | ALDH1A1 (0.38) | ALDH1A1FAAH | |
| SCHEMBL5988216 | 0.74 | — | — | |
| SCHEMBL27741990 | 0.74 | — | — | |
| SCHEMBL20276651 | 0.74 | — | — | |
| SCHEMBL20156542 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360293-B1 | Process for the preparation of 4,5,6,7-tetrahydrothieno[3,2-c]pyridines | LONZA AG (CH) | 1995-08-30 | — | — | EP | claimed |
| US-4990618-A | Process for the production of 4,5,6,7-tetrahydrothieno-[3,2-c]-pyridines | LONZA LTD. (CH) | 1991-02-05 | — | — | US | claimed |
| US-4965359-A | Process for the production of 4,5,6,7-tetrahydrothieno-[3,2-C]-pyridines | LONZA LTD. (CH) | 1990-10-23 | — | — | US | claimed |
| EP-0360293-A2 | Process for the preparation of 4,5,6,7-tetrahydrothieno[3,2-c]pyridines | LONZA AG (CH) | 1990-03-28 | — | — | EP | claimed |
| JP-2134383-A | — | — | None | — | — | JP | disclosed |
| US-20100087485-A1 | 4-AMINOPIPERIDINE DERIVATIVES | BOEHRINGER MARKUS | 2010-04-08 | — | — | US | disclosed |
| US-7683079-B2 | 4-aminopiperidine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2010-03-23 | — | — | US | disclosed |
| EP-1831165-A1 | 4-AMINOPIPERIDINE DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006066747-A1 | 4-AMINOPIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2006-06-29 | — | — | WO | disclosed |
| US-20060135561-A1 | 4-Aminopiperidine derivatives | F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) | 2006-06-22 | — | — | US | disclosed |
| EP-0360293-B1 | Process for the preparation of 4,5,6,7-tetrahydrothieno[3,2-c]pyridines | LONZA AG (CH) | 1995-08-30 | — | — | EP | disclosed |
| US-4990618-A | Process for the production of 4,5,6,7-tetrahydrothieno-[3,2-c]-pyridines | LONZA LTD. (CH) | 1991-02-05 | — | — | US | disclosed |
| US-4990618-A | Process for the production of 4,5,6,7-tetrahydrothieno-[3,2-c]-pyridines | LONZA LTD. (CH) | 1991-02-05 | — | — | US | disclosed |
| US-4965359-A | Process for the production of 4,5,6,7-tetrahydrothieno-[3,2-C]-pyridines | LONZA LTD. (CH) | 1990-10-23 | — | — | US | disclosed |
| JP-H02134383-A | PRODUCTION OF 4,5,6,7-TETRAHYDRO-THIENO-(3,2-C)-PYRIDINE | LONZA AG | 1990-05-23 | — | — | JP | disclosed |
| EP-0360293-A2 | Process for the preparation of 4,5,6,7-tetrahydrothieno[3,2-c]pyridines | LONZA AG (CH) | 1990-03-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087485-A1 | 4-AMINOPIPERIDINE DERIVATIVES | DPP4, GPR119, IAPP | ALDH1A1 199/4885FAAH 2956/4885 |
| US-20060135561-A1 | 4-Aminopiperidine derivatives | DPP4, GPR119, IAPP | ALDH1A1 199/4885FAAH 2956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.