⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3623641 | 0.82 | ALDH1A1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL6331328 | 0.78 | HTR2A (0.42) | — | |
| Hydrochloric Acid SCHEMBL28790221 | 0.77 | SLC6A12 (0.44) | — | |
| SCHEMBL27603777 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL27477535 | 0.75 | — | — | |
| SCHEMBL27741990 | 0.75 | — | — | |
| SCHEMBL5988216 | 0.75 | — | — | |
| SCHEMBL28333223 | 0.75 | — | — | |
| SCHEMBL20156542 | 0.75 | — | — | |
| SCHEMBL1478256 | 0.74 | SLC6A1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0360293-B1 | Process for the preparation of 4,5,6,7-tetrahydrothieno[3,2-c]pyridines | LONZA AG (CH) | 1995-08-30 | — | — | EP | claimed |
| US-4965359-A | Process for the production of 4,5,6,7-tetrahydrothieno-[3,2-C]-pyridines | LONZA LTD. (CH) | 1990-10-23 | — | — | US | claimed |
| EP-0360293-A2 | Process for the preparation of 4,5,6,7-tetrahydrothieno[3,2-c]pyridines | LONZA AG (CH) | 1990-03-28 | — | — | EP | claimed |
| JP-2134383-A | — | — | None | — | — | JP | disclosed |
| EP-0360293-B1 | Process for the preparation of 4,5,6,7-tetrahydrothieno[3,2-c]pyridines | LONZA AG (CH) | 1995-08-30 | — | — | EP | disclosed |
| US-4990618-A | Process for the production of 4,5,6,7-tetrahydrothieno-[3,2-c]-pyridines | LONZA LTD. (CH) | 1991-02-05 | — | — | US | disclosed |
| US-4965359-A | Process for the production of 4,5,6,7-tetrahydrothieno-[3,2-C]-pyridines | LONZA LTD. (CH) | 1990-10-23 | — | — | US | disclosed |
| JP-H02134383-A | PRODUCTION OF 4,5,6,7-TETRAHYDRO-THIENO-(3,2-C)-PYRIDINE | LONZA AG | 1990-05-23 | — | — | JP | disclosed |
| EP-0360293-A2 | Process for the preparation of 4,5,6,7-tetrahydrothieno[3,2-c]pyridines | LONZA AG (CH) | 1990-03-28 | — | — | EP | disclosed |