Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | PTPRC | P08575 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL362411 | 0.88 | CASP6 (0.35) | CASP6SCN9ATDP2NSD2ABL1 | |
| SCHEMBL314058 | 0.80 | TDP1 (0.42) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL20819423 | 0.74 | HPGDS (0.51) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL15951008 | 0.68 | CYP2A6 (0.46) | TDP1HPGDSLTA4HBRD4 | |
| SCHEMBL22557217 | 0.68 | HPGDS (0.40) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL31348092 | 0.68 | TRPV1 (0.40) | HPGDS | |
| SCHEMBL26259970 | 0.67 | SCN9A (0.47) | CASP6SCN9AALDH1A1 | |
| SCHEMBL6206420 | 0.67 | BTK (0.44) | CASP6SCN9A | |
| SCHEMBL1919495 | 0.66 | HPGDS (0.52) | HPGDSLTA4HBRD4ADRA1AADRA2A | |
| SCHEMBL1843737 | 0.66 | KDM4E (0.47) | CASP6SCN9ABLMTDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8097594-B2 | Macrolides and ketolides having antimicrobial activity | WOCKHARDT LTD. (IN) | 2012-01-17 | — | — | US | disclosed |