Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.37 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962040 | 0.76 | LTA4H (0.46) | ADORA3TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16575398 | 0.75 | MAPT (0.41) | ADORA3TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL5252599 | 0.74 | KMT2A (0.40) | ADORA3TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9247248 | 0.74 | KMT2A (0.40) | ADORA3TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7305599 | 0.74 | LTA4H (0.47) | ADORA3KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL7305592 | 0.74 | KMT2A (0.41) | ADORA3TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL16575428 | 0.74 | KMT2A (0.40) | ADORA3TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL91974 | 0.73 | LTA4H (0.48) | KMT2AMAPTMEN1LTA4HNPC1 | |
| SCHEMBL12963218 | 0.72 | TUBB4A (0.63) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL9311655 | 0.72 | KMT2A (0.39) | ADORA3TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1739151-B1 | Mesogenic compounds, liquid crystal medium and liquid display | MERCK PATENT GMBH (DE) | 2010-09-15 | — | — | EP | disclosed |
| EP-1739151-A1 | Mesogenic compounds, liquid crystal medium and liquid display | MERCK PATENT GmbH (DE) | 2007-01-03 | — | — | EP | disclosed |