Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2092369 | 0.86 | PLA2G2A (0.54) | KMT2AMAPTMEN1ALDH1A1TP53 | |
| SCHEMBL16575398 | 0.80 | MAPT (0.41) | KMT2AADORA3MAPTCA12CA1 | |
| SCHEMBL5252599 | 0.78 | KMT2A (0.40) | KMT2AADORA3MAPTCA12CA1 | |
| SCHEMBL7305599 | 0.78 | LTA4H (0.47) | KMT2AADORA3MAPTKDM4EMEN1 | |
| SCHEMBL9247248 | 0.78 | KMT2A (0.40) | KMT2AADORA3MAPTCA12CA1 | |
| SCHEMBL16575428 | 0.78 | KMT2A (0.40) | KMT2AADORA3MAPTCA12CA1 | |
| SCHEMBL91974 | 0.78 | LTA4H (0.48) | KMT2AMAPTCA12CA1CA2 | |
| SCHEMBL3625286 | 0.78 | KMT2A (0.53) | KMT2AMAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL7307663 | 0.78 | CA12 (0.46) | KMT2AMAPTCA12CA1CA2 | |
| SCHEMBL9311655 | 0.77 | KMT2A (0.39) | KMT2AADORA3MAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5629406-A | AMINO ACID DERIVATIVES | SANKYO COMPANY, LIMITED (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0587311-A1 | Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1994-03-16 | — | — | EP | disclosed |